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This page will be available by 1 August 2018
This page will be available by 1st October 2018
Dr. Mohamed Abu-farha
Biochemistry & Molecular Biology Unit
Dasman Diabetes Institute
Dr. Abu-Farha is currently working as scientist at DDI, where for the past five years he has been studying the role of various biomarkers in diabetes and obesity using molecular biology, mass spectrometry, and other protein and lipid related techniques in order to explore their role in diabetes and other metabolic disorders. His primary interest has been, studying the role of betatrophin in diabetes and obesity in regulating beta-cells and lipid metabolism. I am also interested in the interplay between this protein and other members of the ANGPTL family, in particular ANGPTL3, 4. He has published over 30 papers relating to proteomics, diabetes and obesity. He also received many prestigious Canadian national awards from agencies such as NSERC, OGS, and CIHR. More recently, he has been appointed as an associate editor with the journal Frontiers in Endocrinology.
Dr. Abu-Farha have been the principal investigator on a number of projects investigating the role of various biomarkers in diabetes and obesity-linked pathways, such as insulin signaling and lipid metabolism. This research has resulted in over twenty published papers. We have been focused on the role of betatrophin/ANGPTL8 and other members of the ANGPTL family in such key metabolic pathways as lipid metabolism and insulin resistance, and are currently investigating the interactions among ANGPTL3, 4, and 8 in the regulation of triglyceride metabolism through the inhibition of lipoprotein lipase activity, both in vitro and in humans. This work has been fruitful, resulting in a number of publications in international journals including Scientific Reports and Cardiovascular Diabetology.