Pediatrics (107 News)

Three Mutations Collaborate to Induce Congenital heart Disease

Jun 25, 2019 11:00 am
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Congenital heart disease occurs in up to 1% of live births, and the infants who are affected may require multiple surgeries, life-long medication, ...

Paternal Smoking Increases Methylation of Certain Immune Genes Which May Cause Asthma

Jun 23, 2019 2:00 pm
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Children exposed to paternal tobacco smoking before birth are more likely to develop asthma—and associated changes to immune genes predict the l...

Smad7 and β-catenin Genes Play a Role in Muscle Cellular Gene Expression and Differentiation

Jun 19, 2019 3:00 pm
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York University scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation which could...

A Combination of Two Mutations Causes a Deadly Form of Pediatric Brain Tumors

Jun 3, 2019 12:00 pm
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A new Northwestern Medicine study finds that a combination of two mutations cause a form of pediatric brain tumors to become more deadly, according to...

Different Copy Number Variants Have Similar Impacts on Developmental and Psychiatric Health in Children

May 18, 2019 2:00 pm
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Deletions and duplications of DNA are responsible for wide-ranging developmental difficulties in children, finds a new study by Cardiff University....

Anti-ACVR1 Activity Drugs Could Be the Treatment of "Diffuse Intrinsic Pontine Glioma"

May 15, 2019 3:00 pm
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A new type of drug that targets a genetic weakness in an untreatable childhood brain cancer could become the first ever treatment designed to targe...

Researchers Suggest That Inhibiting MYC Protein Can Stop Malignant Rhabdoid Tumor in Childs

May 8, 2019 1:00 pm
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Malignant rhabdoid tumor (MRT) is one of the most aggressive and lethal childhood cancers. Although rare—about 20 to 25 new cases are diagnosed...

Gene Therapy Restores Immunity in Infants with X-SCID

Apr 30, 2019 3:00 pm
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A small clinical trial has shown that gene therapy can safely correct the immune systems of infants newly diagnosed with a rare, life-threatening inhe...

A New Hope for Treatment of Necrotizing Enterocolitis by Inhibiting The ROCK

Apr 30, 2019 11:00 am
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Cutting-edge discovery in the lab of Catherine Hunter, MD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children&...

Chronic Nicotine Exposure During Pregnancy May Alter Pathways of Neurons in Newborns

Apr 28, 2019 1:00 pm
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The Akay Lab biomedical research team at the University of Houston is reporting in the journal Nature Scientific Reports that a possible cure for addi...

Genetic Variants in SRC-1 gene May Be the Cause of Obesity in Children

Apr 21, 2019 12:00 pm
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Maintaining a healthy body weight is no simple matter. A better understanding of how the body regulates appetite could help tip the scale toward th...

A New Sophisticated Computational Model for Diagnosing Rare Hereditary Conditions

Apr 11, 2019 2:00 pm
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London Health Sciences Centre - A new sophisticated computational model, developed by scientists at Lawson Health Research Institute, is bringing a...

Early Life Exposure to Microbiota Is Important for the Development of a Balanced Immune System

Apr 10, 2019 1:00 pm
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Microbes colonize all body surfaces and help to balance the immune system. In newborn infants, gut microbiota is first conditioned by breast milk c...

Aggressive Neuroblastomas Require the Interaction of the MYCN with BRCA1 to Keep the Tumour Alive

Apr 7, 2019 2:00 pm
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Two proteins work hand in hand to ensure that the tumor cells of the neuroblastoma can grow at full speed. How they accomplish this is demonstrated...

Genetic Profiling of Pediatric Cancers to Enhance Personalized Medicine

Apr 4, 2019 1:00 pm
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Research performed over the last several decades has led to an increased understanding of the genetics of cancer. The clinical application of t...

Researchers Detect Maternal Antibodies in Prenatal Babies

Apr 3, 2019 12:00 pm
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Even premature babies carry anti-viral antibodies transferred from the mother, researchers at Karolinska Institutet in Sweden report in a paper on ...

A Gene Commonly Mutated in Pediatric Melanoma is Revealed

Mar 18, 2019 12:00 pm
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Comprehensive clinical genomic testing of an adolescent patient, including whole genome sequencing, helped researchers identify mutations in a sing...

Mutations in Antibodies May Heightened the Risk of Allergic Diseases in Children

Mar 12, 2019 3:00 pm
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A team of researchers from Stanford University, the University of Cincinnati, Children's Hospital Medical Center and the Garvan Institute of Me...

Finding The Genetic Variants That Influence Head Circumference and Intracranial Volume

Jan 26, 2019 2:00 pm
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Children's heads expand steadily to accommodate their growing brains and doctors routinely measure head circumference during the first years of...

Researchers Identify a Rare Genetic Brain Disorder

Jan 26, 2019 1:00 pm
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An international team of researchers, led by MCRI, have identified a rare genetic brain disorder that causes severe neurological damage in children...


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