Molecular Pharmacology (181 News)

A New Tiny DNA Reader to Advance Anticancer Drugs Development

Mar 21, 2019 12:00 pm
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DNA is small. Really, really, small. So, when researchers want to study the structure of a single-stranded DNA, they can’t just pull out thei...

New Small Molecule Inhibitors Show Potential for Treatment of Epstein-Barr Virus-Associated Cancers

Mar 14, 2019 2:00 pm
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Researchers at The Wistar Institute have created a drug candidate for cancers associated with Epstein-Barr Virus (EBV), the virus that causes infec...

A New Drug Combination Could Boost The Effects of Immunotherapy

Mar 14, 2019 12:00 pm
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Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients b...

Existing Drug May Have Potential to Treat Mitochondrial Disease

Mar 12, 2019 4:00 pm
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New preclinical findings from extensive cell and animal studies suggest that a drug already used for a rare kidney disease could benefit patients w...

A New 'Checkpoint' Points to New Cancer Immunotherapy Option

Mar 11, 2019 1:00 pm
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An international team involving Vanderbilt researchers has discovered that a new “checkpoint” protein on immune system cells is active ...

How Could "Diet Drugs" Make Mosquitoes More satisfied and Safer to Be Around?

Mar 10, 2019 5:00 pm
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Now, researchers have discovered a way to stop mosquitoes biting — by using human ‘diet’ drugs to trick them into feeling full. T...

Genetic Engineering Promises to Improve Bone Marrow Transplants

Mar 10, 2019 1:00 pm
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Queensland researchers have conducted Australia’s first clinical trial using genetically engineered immune cells to make bone marrow transpla...

Further Progress for Patients with HER2+ Breast Cancer

Mar 4, 2019 1:00 pm
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In patients with HER2-positive early breast cancer and residual disease after neoadjuvant chemotherapy, adjuvant treatment with trastuzumab emtansi...

Researchers Discover a New Mechanism for a Class of Anti-Cancer Drugs by Revealing 3D Protein Structure

Feb 24, 2019 1:00 pm
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A research team at the Medical University of South Carolina (MUSC) has discovered a new mechanism for a class of anti-cancer drugs known as E1 inhi...

Identifying a New Target Protein Which Can Inhibit Destructive Effects in Tuberculosis

Feb 21, 2019 12:00 pm
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Tuberculosis treatment still entails the administration of several antibiotics over a period of months and is torturous for many patients. The path...

Immunotherapy Can Be Effective in Treating People With Recurrent Glioblastoma

Feb 16, 2019 4:00 pm
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A UCLA-led study suggests that for people with recurrent glioblastoma, administering an immunotherapy drug before surgery is more effective than us...

Commonly Used Anti-Rejection Drug Could Be Re-purposed to Treat Some Liver Cancers

Feb 13, 2019 4:00 pm
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Research from the University of Pittsburgh School of Medicine in animal models and patient tissues has identified a new molecular pathway in the li...

Scientists Successfully Synthesize A Molecule That Can Exhibit Compatible Activities to Natural Molecules

Feb 11, 2019 12:00 pm
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Growth factors are ligands that play important roles in the body – they are responsible for tissue regeneration, wound healing, and the maint...

A Drug Currently Used Might Be Effective in Treating Two Different Types of Cancer

Feb 9, 2019 12:00 pm
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Two new papers, published simultaneously in Nature Communications and led by researchers at McGill University, offer promise that a drug currently ...

New Compound Made of Cellular Prion Protein Shows Promise in Treatment of Alzheimer’s

Jan 10, 2019 4:00 pm
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Yale researchers have identified a drinkable cocktail of designer molecules that interferes with a crucial first step of Alzheimer’s and even...

Researchers Unlock Several Large Gene Clusters by Enticing Away the Repressors Dampening Silent Genes

Jan 6, 2019 4:00 pm
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CHAMPAIGN, Ill. — By enticing away the repressors dampening unexpressed, silent genes in Streptomyces bacteria, researchers at the University...

Injection of Short RNA Molecule Improves Vision in Leber Congenital Amaurosis

Dec 27, 2018 2:00 pm
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PHILADELPHIA -- A new treatment for patients with a form of congenital retinal blindness has shown success in improving vision, according to result...

Experimental Alzheimer's Drug "A03" Enhances Memory in Mice

Dec 25, 2018 2:00 pm
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FINDINGS An experimental drug known as A03, which was previously developed to treat depression, increases the levels of the enzyme Sirtuin1, or S...

Stearoyl CoA Desaturase Enzyme as a Target for Parkinson Treatment

Dec 6, 2018 12:00 pm
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The human brain is rich in lipids. Investigators studying Parkinson's disease (PD) have become increasingly interested in lipids since both mol...

Could HPV Be Treated by A Cancer Drug?

Dec 4, 2018 10:00 am
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Preclinical experiments by University of Alabama at Birmingham researchers suggest the cancer drugs vorinostat, belinostat and panobinostat might b...


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