Study Identifies a Common Bacterial Cause of Gum Disease That May Drive Rheumatoid Arthritis

بكتريا التهاب اللثة قد تسبب التهاب المفاصل الروماتويدي

The oral pathogen Aggregatibacter actinomycetemcomitans (Aa) links periodontal disease and rheumatoid arthritis (RA) by generating citrullinated autoantigens. The figure shows periodontal disease on the right and a rheumatoid joint on the left. The periodontal pathogen Aa (shown in the magnification) drives the production of citrullinated proteins, which initiate an antibody response. Anti-citrullinated protein antibodies (ACPAs) and citrullinated antigens spark the immune system, driving the cascade of events leading to RA. Credit: Felipe Andrade

العربية

Share:

Submitted by: MEMBS,

Dec 19, 2016-6:39 am
965
Views
0
Comments
ID
A00000-BA16-07325