It's not just what you eat, it's what's eating you

With disease, when you decrease autophagy the disease process is exacerbated and when you increase it you get the opposite effect. Aggregation of polyglutamine expansion protein is a hallmark of Huntington's disease and other neurodegenerative diseases. The picture shows that there are more aggregates of green fluorescence protein-labelled polyglutamine expansion protein in autophagy deficient worms (right) compared to normal animals (left). Credit: Florida Atlantic University

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