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The Relationship Between Sex Hormones and Cardiovascular Disease in Post- Menopausal Women

Jul 10, 2018 2:00 pm

In post-menopausal women, having a higher blood level of a male hormone (testosterone) and a higher ratio of the male-type to-female type (estrogen) of hormones is associated with a higher risk of ...

The Secret of Long, Healthy and Cancer free Life of Bats

Jun 28, 2018 4:00 pm

Bats are some of the longest-lived mammals in the world relative to their size. Professor Emma Teeling and her team studied bat telomeres, the caps at the end of chromosomes, in search of longevity...

Uncovering One of the Secrets of Cellular Aging , a Gene Leads to Senescence by Stopping Cells from Dividing

Jun 27, 2018 10:00 am

Scientists seeking to unlock the secrets of cellular aging have identified a gene that triggers senescence, a phenomenon in which cells stop dividing. Senescence is a natural occurrence in the...

Arthrology (4)

a World With NO Arthritis

Feb 15, 2018 12:00 pm

There may come a time when people won’t require surgery to replace their joints. One researcher, Denis Evseenko, MD, Ph.D., a scientist at Keck School of Medicine at the University of Southern C...

New Subset Of T-Cells Implicated in Rheumatoid arthritis

Feb 11, 2017 2:00 pm

A research team led by scientists from Brigham and Women's Hospital (BWH) has carefully scrutinized the immune cells from patients with rheumatoid arthritis, revealing a striking new subset of T-c...

Fibroblasts CouldProvide New Target for Treatment of Rheumatoid Arthritis

Dec 20, 2016 8:05 am

A study led by researchers at the University of Birmingham reveals the key role of different types of fibroblast cells in the development of rheumatoid arthritis (RA), opening up a new avenue for rese...

Bacteriology (246)

A New Enzyme with an Abnormal Amino Acid in its Structure

Jul 14, 2018 12:00 pm

University of Groningen chemists have created a new enzyme with an unnatural amino acid as its active centre. They made the enzyme by modifying an antibiotic binding protein which normally acts as a b...

Highlighting Structural and Kinetic Details of T- box riboswitches in Bacteria

Jul 10, 2018 4:00 pm

In a discovery that points to potential new antibiotic medicines, scientists from Rice University and the University of Michigan have deciphered the workings of a common but little-understood bacte...

A Toxin Discovered in V. Cholera Affects Both Vertebrates and Invertebrates

Jul 10, 2018 12:00 pm

The structure and function of a previously unknown toxin in the cholera bacteria Vibrio cholera has been discovered by scientists at Umeå University, Sweden. The bacterium Vibrio cholerae w...

Bioinformatics (186)

New Insights into the Mechanisms Leading to Cancer Include the Study of Regulatory Regions in the Human Genome

Jul 19, 2018 1:00 pm

A large-scale study provides new insights into the mechanisms that can lead to cancer. It can happen when genes mutate, but cancer also can occur when the genetic regions involved in regulating gen...

The OncoDNA Project Aims to Validate the Unique SaaS Drug Program

Jul 17, 2018 11:00 am

OncoDNA (“OncoDNA or “the Company”), the healthcare technology company making precision medicine a reality, provides an update today on Moncodaneum, a project aimed at validating the...

Two MicroRNA Biomarkers That Can Provide Insights Regarding a Bladder Cancer Prognosis and Treatment

Jul 14, 2018 10:00 am

A potential new target for treatment has been identified in an aggressive form of bladder cancer, Mount Sinai researchers report. The cancer, called p53-like bladder cancer, is named after an activ...

Biopharmaceuticals (83)

New Noninvasive Technique for Precisely Controlling Brain Circuits Could One Day Help Treat Neurological Conditions

Jul 21, 2018 10:00 am

In the maze of our brains, there are various pathways by which neural signals travel. These pathways can go awry in patients with neurological and psychiatric diseases and disorders, including epileps...

New Study Showed Discovered small molecules Which Are Targeting A Specific Protein in Autoinflammatory Diseases

Jul 21, 2018 9:00 am

EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory ...

Could We Treat Cancer Using Herbal Medicine?

Jul 16, 2018 12:00 pm

Researchers from KAUST have been searching locally for plants that have potential for use to combat cancer. They have identified three plants that used for traditional medicine in Saudi Arabia are ...

Biotechnology (296)

The Underlying Cause Behind the Failure of CRISPR Gene Editing and How to Make the Process More Efficient

Jul 22, 2018 1:00 pm

Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient. CRISPR i...

Genome Editing of PCSK9 in Liver Leads to Stable Reduction in Serum Cholesterol

Jul 22, 2018 10:00 am

Genome Editing Reduces Cholesterol in Large Animal Model, Laying the Groundwork for In-Human Trials. Penn study finds genome editing in non-human primates highlights opportunities and challenges fo...

Aproval of First Artificial Iris to Treat Iris Defects that Reduce Sensitivity to Bright Light and glare

Jul 15, 2018 4:00 pm

The US Food and Drug Administration (FDA) has approved the first artificial iris for use in adults and children with congenital aniridia or iris defects due to other reasons or conditions, such as alb...

Cancer (920)

New Insights into the Mechanisms Leading to Cancer Include the Study of Regulatory Regions in the Human Genome

Jul 19, 2018 1:00 pm

The Significance of MGMT Promoter Methylation Status in Predicting Survival Outcomes in Patients with Gliomas

Jul 19, 2018 11:00 am

A DNA-level biomarker (MGMT promoter methylation) can be used to help predict survival outcomes in patients with high-risk, low-grade gliomas, according to a new study conducted through the NRG Onc...

A Base-Independent Mechanism Can Decrease the Photostability of the RNA Base Uracil

Jul 19, 2018 10:00 am

Researchers led by Regina de Vivie-Riedle, a professor of theoretical chemistry at LMU Munich, have found indications for a base-independent mechanism that can decrease the photostability of the RN...

Cancer Therapy (340)

The Significance of MGMT Promoter Methylation Status in Predicting Survival Outcomes in Patients with Gliomas

Jul 19, 2018 11:00 am

The OncoDNA Project Aims to Validate the Unique SaaS Drug Program

Jul 17, 2018 11:00 am

OncoDNA (“OncoDNA or “the Company”), the healthcare technology company making precision medicine a reality, provides an update today on Moncodaneum, a project aimed at validating the...

Increased Public's Interest in Melanoma Testing

Jul 17, 2018 10:00 am

TUESDAY, July 10, 2018 (HealthDay News) -- There is moderately high interest in genetic testing for melanoma risk among the general population, according to a study published in the June issue of JAMA...

Cardiology (152)

Genome Editing of PCSK9 in Liver Leads to Stable Reduction in Serum Cholesterol

Jul 22, 2018 10:00 am

The Relationship Between Sex Hormones and Cardiovascular Disease in Post- Menopausal Women

Jul 10, 2018 2:00 pm

Moving the Cardiac Regulatory Protein RBM20 to the Right Place

Jul 1, 2018 1:00 pm

Tokyo – The largest known protein, the appropriately named titin after the Titan giants of Greek mythology, is a molecular spring found in cardiac muscle. It provides structural support and m...

Cell Biology (467)

Protein Machinery Lies Behind the Development of Highly Aggressive Renal Tumor in Children

Jul 16, 2018 2:00 pm

As cells divide, they must accurately split their DNA between the two daughter cells or risk having an uneven number of chromosomes which can lead to developmental disorders and cancer. A new Donne...

Ferritag .. a New Way to See Proteins Inside Human Cells Using Ferritin

Jul 15, 2018 10:00 am

Scientists at the University of Warwick have created a new way to view proteins that are inside human cells. Using Ferritin, a large protein shell that our cells use to store iron, the researchers ...

Highlighting Structural and Kinetic Details of T- box riboswitches in Bacteria

Jul 10, 2018 4:00 pm

Cell Signaling (127)

Two MicroRNA Biomarkers That Can Provide Insights Regarding a Bladder Cancer Prognosis and Treatment

Jul 14, 2018 10:00 am

A synthetic DNA Enzyme Flips Lipids Causing Cancer Cell Death

Jul 10, 2018 10:00 am

A new synthetic enzyme, crafted from DNA rather than protein, flips lipid molecules within the cell membrane, triggering a signal pathway that could be harnessed to induce cell death in cancer cells. ...

Researchers Use Phosphoproteomics to Obtain Insights into the Brain’s Response to Opioids

Jul 2, 2018 11:00 am

Opioids are powerful painkillers that act on the brain, but they have a range of harmful side effects including addiction. Researchers from the Max Planck Institute of Biochemistry (MPIB) in collab...

Clinical Trials (132)

Genome Editing of PCSK9 in Liver Leads to Stable Reduction in Serum Cholesterol

Jul 22, 2018 10:00 am

An Oral Medication to Replace Chemotherapy for Early-Stage BRCA+ Breast Cancer Patients

Jun 27, 2018 6:00 pm

In a small Phase II study of early-stage breast cancer patients with BRCA1/2 mutations, researchers at The University of Texas MD Anderson Cancer Center found that more than half of the women who t...

A New Therapeutic Selective Inhibitor for CLOVES Syndrome Saves the Patients Major Surgical Interventions

Jun 26, 2018 10:00 am

Dr Guillaume Canaud at the Necker-Enfants Malades Hospital – AP-HP, the Paris Descartes University, Inserm (INEM Institute Necker Enfants Malades – Centre for Molecular Medicine) and hi...

Dentistry (13)

New Promising Period of Craniofacial Genetics

Jun 27, 2018 11:00 am

Our faces can reveal a lot about us, and now scientists are revealing a lot about faces. PLOS Genetics announces a special collection of papers to highlight recent advances in our understanding of ...

Instead of Filling Cavities, Dentists May Soon Regenerate Teeth

Mar 28, 2018 4:00 pm

For dentists, a cavity is a conundrum—in order to save the tooth they must further damage it. Currently, the primary way to treat a cavity is to excavate the decay and the surrounding area befor...

New Innovative Product To Preserve Oral Health

Dec 7, 2017 12:00 pm

Dentists rely on composite materials to perform restorative procedures, such as filling cavities. Yet these materials, like tooth enamel, can be vulnerable to the growth of plaque, the sticky biofilm ...

Dermatology (35)

Asexual Reproduction Is the Rule for Trichophyton Rubrum

Jul 22, 2018 11:00 am

The sexual habits of Trichophyton rubrum, the fungus that causes athlete’s foot and other kinds of skin and nail infections, were the focus of a study published by Brazilian scientists and inter...

Increased Public's Interest in Melanoma Testing

Jul 17, 2018 10:00 am

The Relationship Between Hidradenitis Suppurativa & Crohn's Disease and their Overlapping Features

Jun 28, 2018 5:00 pm

NEW YORK (Reuters Health) - Patients with hidradenitis suppurativa (HS), a skin disorder characterized by painful nodules and abscesses, may be at increased risk for Crohn's disease (CD), and t...

Developmental Biology (141)

The Lack of Bsx Is a New Reason to Disable Sleep-Wake Cycles

Jul 14, 2018 1:00 pm

When zebrafish lack a specific protein, the two hemispheres of the brain develop symmetrically, and the sleep hormone melatonin is not produced. These results were recently published by Freiburg bi...

The Role of Fox Genes in Developing the Face

Jul 5, 2018 8:00 pm

In the developing face, how do stem cells know whether to become cartilage, bones or teeth? To begin to answer this question, scientists from the USC Stem Cell laboratory of Gage Crump tested the r...

Zebrafish Widen Our Scope of Understanding for Congenital Heart Defects

Jun 27, 2018 3:30 pm

Heart defects are the most common congenital defect, yet scientists still struggle to understand why they occur. A new study from the Max Delbruck Center for Molecular Medicine investigates a signa...

Diabetes (113)

Caffeine as a Treatment for Diabetes

Jul 10, 2018 11:00 am

A new study led by researchers from ETH Zurich and the University of Basel in Switzerland and Institut Universitaire de Technologie in France has shown that cells engineered to produce insulin control...

Why Should You Turn off Lights During Night Sleep?

Jun 30, 2018 5:00 pm

According to preliminary results from a new study, nighttime light exposure during sleep may affect metabolic function. The aim of this study was to test the hypothesis that light exposure at night...

An Implant Releases Diabetes Medication When Sensing Caffeine in the Blood

Jun 23, 2018 4:00 pm

Scientists have developed an implant which releases diabetes medication when it senses caffeine in the blood The days of the insulin pen may be numbered. According to researchers in Switzerland, ...

Diseases (790)

The Influential Genetic Factors in Brain Energy Conversion and Their Role in Alzheimer's Disease

Jul 22, 2018 12:00 pm

The strongest genetic risk factor for Alzheimer's disease may impair the brain's ability to convert its primary fuel source into usable energy, finds a study of female mice published in JNeuro...

Asexual Reproduction Is the Rule for Trichophyton Rubrum

Jul 22, 2018 11:00 am

The sexual habits of Trichophyton rubrum, the fungus that causes athlete’s foot and other kinds of skin and nail infections, were the focus of a study published by Brazilian scientists and inter...

Genome Editing of PCSK9 in Liver Leads to Stable Reduction in Serum Cholesterol

Jul 22, 2018 10:00 am

Embryology (2)

Gestational Oral Low-Dose Estradiol-17β May Affect DNA Methylation in Embryos and Adult Offspring

Jul 5, 2018 11:00 am

The public debate on endocrine disrupting chemicals (EDCs) -- exogenous substances that have the same or similar effects as endogenous hormones -- has been going on for some time. Chemicals such as...

Study Results Shows that a Blood Sample can Estimate Fetal Age and Follow up Growth

Jun 11, 2018 8:00 pm

Measuring RNA fragments in a pregnant woman’s blood gives a reliable estimate of the baby’s due date and can predict if the baby will arrive prematurely, a Stanford-led team has shown. ...

Endocrinology (34)

Gestational Oral Low-Dose Estradiol-17β May Affect DNA Methylation in Embryos and Adult Offspring

Jul 5, 2018 11:00 am

New Hope for Patients with Neonatal Diabetes by This Miracle Therapeutic Way

Jun 9, 2018 4:00 pm

Over a decade, Emma Matthews has progressed from fearing for her son's life every night to being safe in the knowledge that his diabetes is well managed thanks to the long-term success of "...

The link between Estrogen and Autoimmune Inflammation

Jun 2, 2018 5:00 pm

Women are more prone to the development of autoimmune diseases. The female hormone estrogen is likely to affect the immune system. A team of scientists from Turku Center for Biotechnology and Unive...

Epigenetics (76)

New Insights into the Mechanisms Leading to Cancer Include the Study of Regulatory Regions in the Human Genome

Jul 19, 2018 1:00 pm

Gestational Oral Low-Dose Estradiol-17β May Affect DNA Methylation in Embryos and Adult Offspring

Jul 5, 2018 11:00 am

A Major Error in One of the Most Widely Used Methods in Epigenetics, DIP-seq, Can Cause Misleading Results

Jul 2, 2018 12:00 pm

In principle, every cell in our body has the same DNA sequence. However, different cell types use very different groups of genes. This means that additional signals are required to control which ge...

Evolution (113)

Building Genomes of Great Apes from Scratch as a Better Resource for Novel Gene Discovery

Jul 14, 2018 2:00 pm

New, higher-quality assemblies of great ape genomes have now been generated without the guidance of the human reference genome. The effort to reduce "humanizing" discovery bias in great a...

Molecular Vestiges Responsible for Testicular Descent in African Mammals

Jul 5, 2018 9:00 pm

The loss of anatomical features is a frequent evolutionary event. For example, humans and other great apes have lost their tail and whales have lost their legs. The most convincing evidence comes f...

From Freaks of Nature to Evolutionary Innovators, Giant Viruses Continue to Shake Branches on the Tree of Life

Jul 5, 2018 4:00 pm

Three new members have been isolated and added to the Pandoravirus family by researchers at the Structural and Genomic Information Laboratory (CNRS/Aix-Marseille Université), working with pa...

Featured (528)

The Underlying Cause Behind the Failure of CRISPR Gene Editing and How to Make the Process More Efficient

Jul 22, 2018 1:00 pm

Genome Editing of PCSK9 in Liver Leads to Stable Reduction in Serum Cholesterol

Jul 22, 2018 10:00 am

Hexakisphosphate Helps HIV Avoid Destroying by the Host’s Immune System

Jul 21, 2018 11:00 am

Scientists from UNSW Sydney and the UK have discovered that the human immunodeficiency virus (HIV) hijacks a small molecule from the host cell to protect itself from being destroyed by the host’...

Gastroenterology (62)

Targeting TRPV4 Receptors for Diarrhea Treatment in Chemotherapy Patients

Jul 9, 2018 10:00 am

Some 50 to 80 percent of cancer patients taking powerful chemotherapy drugs develop diarrhea, which can be severe and in some cases life-threatening. Their problems occur when contractions in the smoo...

The Relationship Between Hidradenitis Suppurativa & Crohn's Disease and their Overlapping Features

Jun 28, 2018 5:00 pm

NEW YORK (Reuters Health) - Patients with hidradenitis suppurativa (HS), a skin disorder characterized by painful nodules and abscesses, may be at increased risk for Crohn's disease (CD), and t...

Described for The First Time, The Regulatory Mechanism for Salmonella Virulence

Jun 9, 2018 5:00 pm

A series of small RNA fragments are the regulator factors involved in a new control mechanism for salmonella virulence, a pathogenic bacterium which causes bacterial gastroenteritis with a high inc...

Gene Therapy (85)

Genome Editing of PCSK9 in Liver Leads to Stable Reduction in Serum Cholesterol

Jul 22, 2018 10:00 am

Groundbreaking Discovery about Metastasis Genes

Jul 15, 2018 4:00 pm

A groundbreaking discovery by University of Alberta researchers has identified previously-unknown therapeutic targets that could be key to preventing the spread of cancer. In a new study published ...

Gene Therapy Finds Its Way to Cure Kidney Cells

Jul 15, 2018 9:00 am

Gene therapy has gained momentum in the past year, following the federal government’s approval of the first such treatments for inherited retinal diseases and hard-to-treat leukemia. Now, resear...

General (312)

Genetically Engineered Food Invading Markets !!

Jun 28, 2018 4:30 pm

While there’s currently no evidence that genetically modified organisms harm human health, that isn’t to say there aren’t legitimate reasons to avoid them. Perhaps the most c...

Sexual Selectivity of Female Fruit Flies isn't Just About Physical Attractiveness !!

Jun 23, 2018 12:00 pm

Researchers at The University of Western Australia have demonstrated the sexual attractiveness of male fruit flies isn't just about how big they are or how nice they smell; it's also about ...

Public Concern about Health Risks of Genetic Engineering and Absence of Politicians on the Scene

Jun 21, 2018 2:00 pm

While a many Danes question whether genetically modified foods are unnatural, this concern is much less apparent among politicians, according to Professor Jesper Lassen at the University of Copenha...

Genetic Diseases (244)

Genome Editing of PCSK9 in Liver Leads to Stable Reduction in Serum Cholesterol

Jul 22, 2018 10:00 am

Increased Public's Interest in Melanoma Testing

Jul 17, 2018 10:00 am

Protein Machinery Lies Behind the Development of Highly Aggressive Renal Tumor in Children

Jul 16, 2018 2:00 pm

Genetics (1157)

The Underlying Cause Behind the Failure of CRISPR Gene Editing and How to Make the Process More Efficient

Jul 22, 2018 1:00 pm

The Influential Genetic Factors in Brain Energy Conversion and Their Role in Alzheimer's Disease

Jul 22, 2018 12:00 pm

The strongest genetic risk factor for Alzheimer's disease may impair the brain's ability to convert its primary fuel source into usable energy, finds a study of female mice published in JNeuro...

Asexual Reproduction Is the Rule for Trichophyton Rubrum

Jul 22, 2018 11:00 am

The sexual habits of Trichophyton rubrum, the fungus that causes athlete’s foot and other kinds of skin and nail infections, were the focus of a study published by Brazilian scientists and inter...

Genome & Genomics (298)

Genome Editing of PCSK9 in Liver Leads to Stable Reduction in Serum Cholesterol

Jul 22, 2018 10:00 am

Protein Machinery Lies Behind the Development of Highly Aggressive Renal Tumor in Children

Jul 16, 2018 2:00 pm

Sheding More Light on the Communication Between Different Chromosomes

Jul 16, 2018 11:00 am

How are chromosomes arranged in the cell nucleus? Is it possible that they communicate with one another by "touching" each other? To answer this question and to shed more light on the fun...

Gynecology (44)

A Genetic Variation in Progesterone Receptor Might Be Linked to Prematurity Risk

Jun 30, 2018 2:00 pm

Humans have unexpectedly high genetic variation in the receptor for a key pregnancy-maintaining hormone, according to research led by scientists at the Stanford University School of Medicine. The f...

Study Results Shows that a Blood Sample can Estimate Fetal Age and Follow up Growth

Jun 11, 2018 8:00 pm

Measuring RNA fragments in a pregnant woman’s blood gives a reliable estimate of the baby’s due date and can predict if the baby will arrive prematurely, a Stanford-led team has shown. ...

Prominent Interaction between Schizophrenia Associated Genes and History of Serious Pregnancy Complications

Jun 10, 2018 7:00 pm

Hiding in plain sight, new research shines a spotlight on the placenta's critical role in the nature versus nurture debate and how it confers risk for schizophrenia and likely other neurodevelo...

Hematology (96)

Location of Blood Stem Cells in the Bone Is a Guarantee against UV Radiation

Jul 15, 2018 5:00 pm

Stem cell scientists at Harvard University and Boston Children’s Hospital have shown that the location of blood stem cells in the body — their 'niche' — evolved to protect th...

New FDA Approval for a Drug that Stimulates Platelet Production

Jul 9, 2018 4:00 pm

The US Food and Drug Administration (FDA) has approved avatrombopag (Doptelet, AkaRx Inc) to increase platelet counts in adults with thrombocytopenia and chronic liver disease who are to undergo a pla...

Non Invasive DNA Blood Test to Detect Cancer at Early Stages

Jul 9, 2018 3:00 pm

(CNN) Promising new research enables scientists to use a blood test to screen for different types of cancers at early stages. The test, known as a liquid biopsy, is used to screen for DNA from...

Histopathology (11)

A New Enzyme with an Abnormal Amino Acid in its Structure

Jul 14, 2018 12:00 pm

How Oncogenic Mutant Cells Lead The War Against Normal Ones To Expand Its Property in Tissue?

Jun 24, 2018 11:00 am

Cells in multicellular tissues adhere to each other. Epithelial tissues on the surface layer of the intestines and skin pack cells into a hexagonal (honeycomb) pattern, with cells adhering tightly ...

Surprising Discoveries Limit the Importance of Apoptosis in Embryonic Development

May 23, 2018 10:00 am

Australian researchers have made a surprise discovery that could rewrite our understanding of the role programmed cell death plays in embryonic development and congenital birth defects. The team sh...

Immunology (384)

Hexakisphosphate Helps HIV Avoid Destroying by the Host’s Immune System

Jul 21, 2018 11:00 am

Scientists from UNSW Sydney and the UK have discovered that the human immunodeficiency virus (HIV) hijacks a small molecule from the host cell to protect itself from being destroyed by the host’...

New Study Showed Discovered small molecules Which Are Targeting A Specific Protein in Autoinflammatory Diseases

Jul 21, 2018 9:00 am

Generating Mice That Express the Human NTCP Protein in Their Liver Cells, Allowing HBV and HDV Infections

Jul 11, 2018 9:00 am

Hepatitis delta virus (HDV) causes the most aggressive form of viral hepatitis in humans, putting at least 20 million people worldwide at risk of developing liver fibrosis, cirrhosis, and liver cancer...

Infectious Diseases (128)

Hexakisphosphate Helps HIV Avoid Destroying by the Host’s Immune System

Jul 21, 2018 11:00 am

Scientists from UNSW Sydney and the UK have discovered that the human immunodeficiency virus (HIV) hijacks a small molecule from the host cell to protect itself from being destroyed by the host’...

Generating Mice That Express the Human NTCP Protein in Their Liver Cells, Allowing HBV and HDV Infections

Jul 11, 2018 9:00 am

A Toxin Discovered in V. Cholera Affects Both Vertebrates and Invertebrates

Jul 10, 2018 12:00 pm

The structure and function of a previously unknown toxin in the cholera bacteria Vibrio cholera has been discovered by scientists at Umeå University, Sweden. The bacterium Vibrio cholerae w...

Infertility (29)

A New Function of FGF2 May Contribute to Treating Infertility in Males

Jul 12, 2018 10:00 am

A research team found a novel function of "FGF2", growth factor for spermatogonial stem cells (SSCs) which is the origin of the sperm. This study was published online in "Stem Cell R...

Gestational Oral Low-Dose Estradiol-17β May Affect DNA Methylation in Embryos and Adult Offspring

Jul 5, 2018 11:00 am

New Study Reveals the Biological Mechanisms Affecting mtDNA Inheritance

Jul 2, 2018 10:00 am

A new study has shed light on how deadly genetic diseases may be inherited, according to research published today (27/06/2018) from a project led by the University of Birmingham, Imperial College L...

Microbiology (189)

Highlighting Structural and Kinetic Details of T- box riboswitches in Bacteria

Jul 10, 2018 4:00 pm

A Toxin Discovered in V. Cholera Affects Both Vertebrates and Invertebrates

Jul 10, 2018 12:00 pm

The structure and function of a previously unknown toxin in the cholera bacteria Vibrio cholera has been discovered by scientists at Umeå University, Sweden. The bacterium Vibrio cholerae w...

Scientists Recreate Aspects of Real Ecosystem to Spur Dormant and Hidden Antibiotic Capacities into Action

Jul 9, 2018 5:00 pm

Alexander Fleming's discovery of penicillin—the world's first natural antibiotic—is famously told as a story of serendipity: a petri dish growing bacteria was contaminated by mo...

Molecular Biochemistry (469)

The Influential Genetic Factors in Brain Energy Conversion and Their Role in Alzheimer's Disease

Jul 22, 2018 12:00 pm

The strongest genetic risk factor for Alzheimer's disease may impair the brain's ability to convert its primary fuel source into usable energy, finds a study of female mice published in JNeuro...

Genome Editing of PCSK9 in Liver Leads to Stable Reduction in Serum Cholesterol

Jul 22, 2018 10:00 am

New Study Showed Discovered small molecules Which Are Targeting A Specific Protein in Autoinflammatory Diseases

Jul 21, 2018 9:00 am

Molecular Pharmacology (161)

New Study Showed Discovered small molecules Which Are Targeting A Specific Protein in Autoinflammatory Diseases

Jul 21, 2018 9:00 am

Treating Breast Cancer and Neurological Conditions by Targeting TLK2

Jul 9, 2018 9:00 am

In recent years, researchers have focused on the enzyme TLK2, suspecting it of playing a main role in several diseases. A new study conducted at the University of Copenhagen now reveals that the enzym...

For the First time Scientists Find Unique Way to Distinguish Between Molecules

Jul 5, 2018 3:00 pm

A University of Central Florida team has designed a nanostructured optical sensor that for the first time can efficiently detect molecular chirality—a property of molecular spatial twist that...

Mycology (8)

Asexual Reproduction Is the Rule for Trichophyton Rubrum

Jul 22, 2018 11:00 am

The sexual habits of Trichophyton rubrum, the fungus that causes athlete’s foot and other kinds of skin and nail infections, were the focus of a study published by Brazilian scientists and inter...

Identification of the Biosynthetic Gene Cluster for Highly Oxygenated Steroids Group Derived from Fungi

Jun 24, 2018 6:00 pm

A group of researchers from Graduate School of Pharmaceutical Sciences at The University of Tokyo and Institute of Traditional Chinese Medicine and Natural Products at Jinan University, identified ...

Fungal Cells Use Surprising Method To Communicate With Each Other!

May 1, 2018 1:00 pm

The idea of microbes joining forces inside your body to wreak havoc and cause disease sounds frightening — and it should. Now, scientists have found that a particular type of fungus does just th...

Nanotechnology (54)

A synthetic DNA Enzyme Flips Lipids Causing Cancer Cell Death

Jul 10, 2018 10:00 am

Researchers Conducted Site-Specific Gene Editing in a Fetus, Correcting a Mutation That Causes Thalassemia

Jun 30, 2018 12:00 pm

With the combined efforts of three Yale laboratories, researchers conducted the first demonstration of site-specific gene editing in a fetus, correcting a mutation that causes a severe form of anem...

Nanophotonics for Detection of Biomarkers in Blood

Jun 12, 2018 9:00 am

Infrared spectroscopy is the benchmark method for detecting and analyzing organic compounds. But it requires complicated procedures and large, expensive instruments, making device miniaturization c...

Neurology (644)

The Influential Genetic Factors in Brain Energy Conversion and Their Role in Alzheimer's Disease

Jul 22, 2018 12:00 pm

The strongest genetic risk factor for Alzheimer's disease may impair the brain's ability to convert its primary fuel source into usable energy, finds a study of female mice published in JNeuro...

New Noninvasive Technique for Precisely Controlling Brain Circuits Could One Day Help Treat Neurological Conditions

Jul 21, 2018 10:00 am

Genetic Differences Shed Light on the Potential Differences in the Risk of Meningitis Among Women and Men

Jul 17, 2018 9:00 am

Glioma is the most common type of primary malignant brain tumor in the United States; glioblastoma being the most common type of glioma in adults. While sex differences in the incidence and survival r...

Nutrition (119)

Using CRISPR gene editing Technology to Boost Productivity of Rice

Jun 4, 2018 4:00 pm

A team of scientists from Purdue University and the Chinese Academy of Sciences has used CRISPR/Cas9 gene-editing technology to develop a variety of rice that produces 25-31 percent more grain and ...

A Molecule in Green tea May Help Make New Medicines to Treat Heart Attack and Stroke

Jun 3, 2018 11:00 am

Scientists from Lancaster University and the University of Leeds have discovered that a compound found in green tea, currently being studied for its ability to reduce amyloid plaques in the brain in A...

New Drug Approved by FDA to Treat PKU " A Rare Genetic Disease"

May 28, 2018 7:00 pm

The US Food and Drug Administration (FDA) has approved pegvaliase-pqpz (Palynziq, BioMarin Pharmaceutical Inc) for adults with phenylketonuria (PKU) whose uncontrolled blood phenylalanine (Phe) concen...

Obesity (97)

A New Way to Control the Formation of Fat Cells Through Cells That Suppress Adipogenesis

Jun 23, 2018 6:00 pm

A study led by researchers in Switzerland has revealed a new cell type that resides in the body’s fat depots where it can actively suppress fat cell formation. This discovery was made using s...

The Gene Involved in Obesity Reveals New Insights into Insulin Activation

Jun 13, 2018 11:00 am

A gene previously linked with obesity has been found to affect how the body processes insulin, with potential implications for some forms of diabetes. Scientists have uncovered a number of gen...

The Role the Gut Plays in Processing and Distributing Fat

Jun 10, 2018 9:00 pm

Research by scientists at King's College London into the role the gut plays in processing and distributing fat could pave the way for the development of personalised treatments for obesity and ...

Ophthalmology (39)

A Genetic Mutation Associated with Neuromyelitis Optica (NMO)

Jun 28, 2018 12:00 pm

Scientists conducting one of the largest full DNA analyses of a rare disease have identified a gene mutation associated with a perplexing brain condition that blinds and paralyzes patients. A ...

The Largest-Ever Genetic Study Identified 161 Genetic Factors for Myopia

Jun 27, 2018 7:00 pm

The international Consortium for Refractive Error and Myopia (CREAM) recently published the largest-ever genetic study of myopia in Nature Genetics. Researchers from the Gutenberg Health Study at t...

A Genetic Analysis Suggests a Link among Requiring Vision Correction, Higher Intelligence, Longevity and Hypertension

Jun 4, 2018 11:00 am

A large international team of researchers has found a link between intelligence and eyesight, longevity and hypertension. In their paper published in the journal Nature Communications, the group de...

Organizations / Institutions (135)

The OncoDNA Project Aims to Validate the Unique SaaS Drug Program

Jul 17, 2018 11:00 am

OncoDNA (“OncoDNA or “the Company”), the healthcare technology company making precision medicine a reality, provides an update today on Moncodaneum, a project aimed at validating the...

New Guidelines from the American Cancer Society about Colorectal Cancer Screening

Jul 16, 2018 4:00 pm

New guidelines from the American Cancer Society (ACS) recommend that colorectal cancer screening begin at a younger age than what is currently recommended. For persons at average risk, screening sh...

Sensitive Biosensor from KAUST Generated by Combining Redox Enzymes with Polymers

Jul 12, 2018 11:00 am

A novel concept for a biosensor of the metabolite known as lactate, combines an electron transporting polymer with lactate oxidase, which is the enzyme that specifically catalyzes the oxidation of ...

Osteology (22)

New Drugs from FDA for Osteoarthritis Pain and Hypertension

Jun 28, 2018 5:30 pm

The US Food and Drug Administration (FDA) approved a combination of amlodipine besylate and the nonsteroidal anti-inflammatory drug (NSAID) celecoxib (Consensi, Kitov Pharma) for individuals with o...

Spinal Stimulation Helps Paralyzed Patients Regain Function

May 5, 2018 10:00 am

Once a person has suffered a spinal cord injury, there isn't much to be done except to learn how to live with paralysis and loss of function. That could change, thanks to the work of a team of sci...

Metastatic Cancer Cells Modify Bone Remodeling With Small RNA Secretion In Bone Metastasis

Mar 29, 2018 10:00 am

Prostate cancer is one of the most common cancers in men worldwide. In nearly three out of four patients the cancer causes metastasis, leaving the original site of the tumor and spreading to distant s...

Otolaryngology (4)

New Technique That Will Force The Centromere To Give Up Its Secrets

Dec 11, 2017 3:00 pm

A new technique may force the centromere -- the mysterious stretch of DNA in the center of every chromosome -- to give up its secrets at last. The first test of the approach has yielded clues about th...

How Sleep Apnea Can Be a Risk Factor for Diabetes?

Sep 19, 2017 10:00 am

Sleep apnea, left untreated for even a few days, can increase blood sugar and fat levels, stress hormones and blood pressure, according to a new study of sleeping subjects. This research adds further ...

Sensory cell regeneration, the new path in treating hearing loss.

May 20, 2017 2:00 pm

In an apparent first, St. Jude Children's Research Hospital investigators have used genetic manipulation to regenerate auditory hair cells in adult mice. The research marks a possible advance in t...

Parasitology (43)

Bone Marrow is a Major Reservoir for P. Vivax Malaria Parasite

Jul 9, 2018 2:00 pm

NEW YORK (Reuters Health) - Beyond blood, bone marrow is a major reservoir of the malaria parasite Plasmodium vivax, according to an international group of researchers. As Dr. Matthias Marti told R...

Two Proteins Recognize and Translate DNA Methylation Marks in Schistosoma Mansoni

Jul 5, 2018 1:00 pm

Two proteins that recognize and translate DNA methylation marks in Schistosoma mansoni are required for growth of adult stem cells in the parasitic flatworm, as well as production of eggs, accordin...

Revealing for the First Time the Evolutionary Path of Plasmodium falciparum !!

Jun 24, 2018 7:00 pm

The evolutionary path of the deadliest human malaria parasite, Plasmodium falciparum, has been revealed for the first time. This parasite is a member of a parasite family called the Laverania that ...

Pediatrics (79)

The Four Trajectories Cancer Cells Take to Escape Immune System

Jun 30, 2018 4:30 pm

Cancer cells in children tend to develop by following four main trajectories - and two of them are linked to relapse of the disease, research led by Lund University in Sweden shows. The four strate...

Study Results Shows that a Blood Sample can Estimate Fetal Age and Follow up Growth

Jun 11, 2018 8:00 pm

Measuring RNA fragments in a pregnant woman’s blood gives a reliable estimate of the baby’s due date and can predict if the baby will arrive prematurely, a Stanford-led team has shown. ...

New Hope for Patients with Neonatal Diabetes by This Miracle Therapeutic Way

Jun 9, 2018 4:00 pm

Over a decade, Emma Matthews has progressed from fearing for her son's life every night to being safe in the knowledge that his diabetes is well managed thanks to the long-term success of "...

Pharmacogenetics (23)

Roche Is Paying Billions of Dollars to Buy the Rest of Foundation Medicine

Jun 26, 2018 1:00 pm

The Swiss drugmaker has clearly noticed the genomic profiling group’s ability to personalise cancer care, now that it will take complete ownership of the company. Roche had already owned...

Predicting the Side Effects of Phenytoin with a New Genetic Test

Jun 25, 2018 9:00 pm

A study led by researchers at RCSI (Royal College of Surgeons in Ireland) has identified a new genetic test that can be used to predict if a patient with epilepsy will develop an adverse reaction t...

"Danger Theory" Helps to Apply A New Therapeutic Drug For SIRS Baised on The Body's Reactions to Its Mitochondria

Jun 21, 2018 10:00 am

The immune response after a traumatic physical injury is essentially the same as a body-wide bacterial infection: inflammatory, systemic, and lethal. From the Medical College of Georgia at Augusta ...

Physiology (20)

Identification of the Cellular Mechanism that Leads to Neurodegeneration in Parkinson’s Disease

Jul 16, 2018 5:00 pm

Northwestern Medicine scientists identified a cellular mechanism that leads to neurodegeneration in patients with Parkinson’s disease, according to a study published in Proceedings of the Nation...

The Lack of Bsx Is a New Reason to Disable Sleep-Wake Cycles

Jul 14, 2018 1:00 pm

A New Function of FGF2 May Contribute to Treating Infertility in Males

Jul 12, 2018 10:00 am

A research team found a novel function of "FGF2", growth factor for spermatogonial stem cells (SSCs) which is the origin of the sperm. This study was published online in "Stem Cell R...

Products & Technologies (572)

The OncoDNA Project Aims to Validate the Unique SaaS Drug Program

Jul 17, 2018 11:00 am

OncoDNA (“OncoDNA or “the Company”), the healthcare technology company making precision medicine a reality, provides an update today on Moncodaneum, a project aimed at validating the...

ThermoFisher Scientific Company Donate 1 Million$ Worth of Rapid DNA Analyzers

Jul 16, 2018 10:00 am

Thermo Fisher Scientific, the world leader in serving science, announced it is offering to donate $1 million worth of rapid DNA analyzers and related technology to support efforts to reunite chi...

Aproval of First Artificial Iris to Treat Iris Defects that Reduce Sensitivity to Bright Light and glare

Jul 15, 2018 4:00 pm

Proteome & Proteomics (29)

Ferritag .. a New Way to See Proteins Inside Human Cells Using Ferritin

Jul 15, 2018 10:00 am

Researchers Use Phosphoproteomics to Obtain Insights into the Brain’s Response to Opioids

Jul 2, 2018 11:00 am

Genomic Atlas for the human blood proteome

Jun 20, 2018 12:00 pm

An international team of researchers led by scientists at the University of Cambridge and MSD has created the first detailed genetic map of human proteins, the key building blocks of biology. These...

Psychology (108)

New Noninvasive Technique for Precisely Controlling Brain Circuits Could One Day Help Treat Neurological Conditions

Jul 21, 2018 10:00 am

Common Genotype for Certain Brain Disorders

Jul 14, 2018 9:00 am

Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers ...

New Genes Associated with Intelligence Have Been Identified

Jul 9, 2018 1:00 pm

Researchers have identified over 1,016 specific genes associated with intelligence, the vast majority of which are unknown to science. An international team conducted a large-scale genetic ass...

Pulmonary & Respiratory Medicine (35)

Researchers Have Identified a Genetic Bio-markers to Test Asthma Simply & Accurately

Jun 20, 2018 8:00 pm

Mount Sinai researchers have identified a genetic biomarker of asthma that can be tested for using a simple nasal brush and basic follow-up data analysis. This inexpensive diagnostic test can accur...

Study Identifies New Molecular Target For Treating The Deadly Lung Disease "IPF"

May 2, 2018 12:00 pm

Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclini...

Genes That Dictate Our Susceptibility To Develop Allergies

Apr 21, 2018 9:00 am

Whether or not you develop an allergy is largely dependent upon genetic factors. This is the main finding of a study recently published in EBioMedicine, just in time for World Allergy Week. The study ...

Regenerative Medicine & Cell Therapy (44)

Grainyhead Protein Orchestrates Gene Transcription

Jun 11, 2018 9:00 pm

A team led by Prof. Stein Aerts (VIB-KU Leuven) uncovers how access to relevant DNA regions is orchestrated in epithelial cells. These findings shed new light on the biological mechanisms of gene r...

A Free Online Kidney Atlas To Empower kidneys Related Stem Cells Research

Apr 19, 2018 3:00 pm

A free online kidney atlas built by USC researchers empowers stem cell scientists everywhere to generate more human-like tiny kidneys for testing new drugs and creating renal replacement therapies. &...

Liver Cells Repair Itself By Expressing Telomerase Enzyme

Apr 11, 2018 10:00 am

Liver stem cells that express high levels of telomerase, a protein often associated with resistance to aging, act in mice to regenerate the organ during normal cellular turnover or tissue damage, acco...

Scientists (7)

Dr. Amin Arnaout Recipient of The Prestigious Homer W. Smith Award

May 15, 2018 9:00 am

Dr. Amin Arnaout has been honored by the American Society of Nephrology (ASN) as recipient of the 2018 Homer W. Smith Award and recognized as “an individual who has made outstanding contribut...

Dr. Al-Zayani Receives The Venus Medical Award at a Ceremony In India

May 2, 2018 2:00 pm

Dr. Salman Hamad Al-Zayani, the Assistant Professor of Public Health at the College of Medicine and Medical Sciences at the Arabian Gulf University (AGU), has received the Venus International Medical ...

The Brain Prize This Year Goes To Alzheimer's Researchers

Mar 11, 2018 9:00 am

Four dementia scientists have shared this year's 1m Euro brain prize for pivotal work that has changed our understanding of Alzheimer's disease. Profs John Hardy, Bart De Strooper, Michel G...

Single Nucleotide Polymorphisms (13)

Low Genetic Diversity Put the Singapore Freshwater Crab Under the Threat of Extinction

Jun 24, 2018 4:00 pm

Researchers from NUS and National Parks Board (NParks) have established that the critically endangered Singapore freshwater crab (Johora singaporensis) does not mix or breed between different popul...

Mendelian Randomization Analysis to More Precision and Less Time and Cost

Jun 7, 2018 1:00 pm

The evolution of medicine relies heavily on the results of clinical trials, which while essential, are extremely costly and carry the potential of unintended adverse consequences. Now researchers from...

Mutations Other Than BRCA Can Cause Second Primary Breast Cancer

Jun 6, 2018 5:00 pm

Rates of inherited mutations in genes other than BRCA1/2 are twice as high in breast cancer patients who have had a second primary cancer—including, in some cases, different types of breast c...

Stem Cells & Cancer Stem Cells (194)

Sheding More Light on the Communication Between Different Chromosomes

Jul 16, 2018 11:00 am

How are chromosomes arranged in the cell nucleus? Is it possible that they communicate with one another by "touching" each other? To answer this question and to shed more light on the fun...

Location of Blood Stem Cells in the Bone Is a Guarantee against UV Radiation

Jul 15, 2018 5:00 pm

Stem cell scientists at Harvard University and Boston Children’s Hospital have shown that the location of blood stem cells in the body — their 'niche' — evolved to protect th...

A New Function of FGF2 May Contribute to Treating Infertility in Males

Jul 12, 2018 10:00 am

A research team found a novel function of "FGF2", growth factor for spermatogonial stem cells (SSCs) which is the origin of the sperm. This study was published online in "Stem Cell R...

Toxicology (30)

A Toxin Discovered in V. Cholera Affects Both Vertebrates and Invertebrates

Jul 10, 2018 12:00 pm

The structure and function of a previously unknown toxin in the cholera bacteria Vibrio cholera has been discovered by scientists at Umeå University, Sweden. The bacterium Vibrio cholerae w...

Studying Glycans in Venom of South American Viper Which May Have Applications in Biotechnology

Jun 4, 2018 3:00 pm

A bite from a lancehead snake can be fatal. Species in the family, found throughout Central and South America, have venom that can disrupt blood clotting and cause hemorrhage, strokes and kidney fa...

Food Packaging Might Cause Dysfunction In The Digestive Tract

Apr 17, 2018 9:00 am

Our digestive system has a complex relationship with our health. Intestinal cells form an important barrier that has to let nutrients in and keep harmful substances out, among other important function...

Transcriptome & Transcriptomics (6)

Discovering the First Genetic Marker for Bone Tumor

Jul 10, 2018 3:00 pm

The first genetic marker for the bone tumour, osteoblastoma, has been discovered by scientists at the Wellcome Sanger Institute and their collaborators. Whole-genome and transcriptome sequencing of hu...

Study Shows How Data-Driven AI Could Help in Prostate Cancer Diagnosis, Treatment and Better Understanding of Its Development

Jul 5, 2018 12:00 pm

Researchers in Sweden have shown how data-driven AI could contribute to a better understanding of how prostate cancer develops, and even improve clinical diagnosis and treatment of the disease. ...

Scientists Develop a Tool Capable of Analyzing the Levels of Gene Expression of Single Cells

Jun 13, 2018 3:00 pm

New research led by Holger Heyn at the Centro Nacional de Análisis Genómico of the Centre for Genomic Regulation (CNAG-CRG), presents a sophisticated computational framework to analyz...

Urology (10)

Disabled Kidney Function May Cause Diabetes

Dec 16, 2017 4:00 pm

Diabetes is known to increase a person's risk of kidney disease. Now, a new study from Washington University School of Medicine in St. Louis suggests that the converse also is true: Kidney dysfunc...

Rare resistance mutation reduces treatment choices for urinary tract infections

Sep 9, 2017 6:00 pm

Nearly 20 percent of women aged 15-29 are diagnosed with a urinary tract infection (UTI). Now, investigators have uncovered a rare mutation that renders a UTI-causing pathogen resistant to levofloxaci...

Cancer drug may benefit patients with inherited form of kidney disease

Sep 4, 2017 4:00 pm

A cancer drug called bosutinib may inhibit the growth of cysts in patients with autosomal dominant polycystic kidney disease (ADPKD), according to a study appearing in an upcoming issue of the Journal...

Vaccines (52)

Novel Approach Has the Potential to Measure the Effectiveness of Bexsero More Accurately

Jun 21, 2018 1:00 pm

Researchers at Leicester and the Meningococcal Reference Unit have developed a new approach to assess the effectiveness of the Men B vaccine, Bexsero®, against different strains that cause meni...

Why Does the Flu Vaccine Work for Some, and Not Other, Genetically Speaking?

May 30, 2018 10:00 am

Each year, 132 million Americans flock to doctors’ offices, pharmacies, and clinics for flu shots. With the onset of “flu season” each year, 41% of the population opts to get ...

Mosquitoes may Increase the Severity of the Diseases they Transmit !!

May 21, 2018 1:00 pm

Mosquito season is around the corner, bringing with it a higher risk of catching potentially serious diseases transmitted by their bite. Mosquitoes also may increase the severity of the diseases they ...

Virology (184)

Hexakisphosphate Helps HIV Avoid Destroying by the Host’s Immune System

Jul 21, 2018 11:00 am

Scientists from UNSW Sydney and the UK have discovered that the human immunodeficiency virus (HIV) hijacks a small molecule from the host cell to protect itself from being destroyed by the host’...

Gene Therapy Finds Its Way to Cure Kidney Cells

Jul 15, 2018 9:00 am

Gene therapy has gained momentum in the past year, following the federal government’s approval of the first such treatments for inherited retinal diseases and hard-to-treat leukemia. Now, resear...

Generating Mice That Express the Human NTCP Protein in Their Liver Cells, Allowing HBV and HDV Infections

Jul 11, 2018 9:00 am

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