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Genoms And Its Roles In Biological Ageing

Sep 29, 2018 10:00 am

Senescence, or biological ageing, refers to the general deterioration of an organism's physiological functions, leading to increased susceptibility to diseases and ultimately death. It is a comple...

The Relationship Between Sex Hormones and Cardiovascular Disease in Post- Menopausal Women

Jul 10, 2018 2:00 pm

In post-menopausal women, having a higher blood level of a male hormone (testosterone) and a higher ratio of the male-type to-female type (estrogen) of hormones is associated with a higher risk of ...

The Secret of Long, Healthy and Cancer free Life of Bats

Jun 28, 2018 4:00 pm

Bats are some of the longest-lived mammals in the world relative to their size. Professor Emma Teeling and her team studied bat telomeres, the caps at the end of chromosomes, in search of longevity...

Arthrology (5)

A Malfunctioning Gene May Associated with Ankylosing Spondylitis

Sep 4, 2018 11:00 am

A new Michigan State University study has found that a malfunctioning gene associated with a common arthritic disease that often starts in teenagers is now directly linked to the loss of vital immu...

a World With NO Arthritis

Feb 15, 2018 12:00 pm

There may come a time when people won’t require surgery to replace their joints. One researcher, Denis Evseenko, MD, Ph.D., a scientist at Keck School of Medicine at the University of Southern C...

New Subset Of T-Cells Implicated in Rheumatoid arthritis

Feb 11, 2017 2:00 pm

A research team led by scientists from Brigham and Women's Hospital (BWH) has carefully scrutinized the immune cells from patients with rheumatoid arthritis, revealing a striking new subset of T-c...

Bacteriology (262)

How the Distance of Microbial Competitions Shapes Their Community Structures?

Dec 8, 2018 10:00 am

Inside the microbial communities that populate our world, microbes are fighting for their lives. These tiny organisms are in the soil, in the oceans, and in the human body. Microbes play sever...

Creating Microbes with an Expanded Genetic Code Can Open Up New Avenues in Synthetic Biology and Protein Engineering

Dec 3, 2018 2:00 pm

Our genetic code is made up of four nucleotide bases, but in recent years, scientists have created microbes that incorporate totally new bases. That has opened up new avenues in synthetic biology a...

New Approach Identifies More Than 6,000 Antibiotic Resistance Genes in Gut Bacteria

Dec 2, 2018 12:00 pm

A study carried out in collaboration with the University of Birmingham has used an innovative approach to identify thousands of antibiotic resistance genes found in bacteria that inhabit the human ...

Bioinformatics (210)

Active and Sedentary Life Is Determined in Part by Our Genes

Dec 11, 2018 5:00 pm

In one of the most detailed projects of its kind, the scientists studied the activity of 91,105 UK Biobank participants who had previously worn an activity monitor on their wrist for a week. T...

Researchers Were Able to Visualize the Proteasome's Inner Workings

Dec 11, 2018 4:00 pm

LA JOLLA, CA – One of a cell’s most important responsibilities is to break down and recycle proteins that are no longer needed or endanger the cell. This task is carried out by a cellul...

A Computer Model Illustrates the Connection between Physical Organization of DNA and Gene Expression

Dec 10, 2018 12:00 pm

Scientists often try to understand important processes in the cell by interfering and observing what happens. But often the cell just dies. That was the problem that Andrew Spakowitz, associat...

Biopharmaceuticals (98)

NSD2 Might Be a Therapeutic Target for Metastatic and Resistant Prostate Cancers

Dec 9, 2018 6:00 pm

A door opens to a new combined therapy to treat the most aggressive and resistant prostate cancers. This is one of the conclusions reached by researchers from the Institute of Biomedical Research o...

AstraZeneca provides Update on GALATHEA Phase III Trial for Fasenra in Chronic Obstructive Pulmonary Disease

Oct 10, 2018 9:00 am

AstraZeneca and MedImmune, its global biologics research and development arm, today announced top-line results from the GALATHEA Phase III trial for Fasenra (benralizumab) in patients with moderate...

Lumoxiti, the First New Treatment Option for HCL's Patients in Over 20 Years

Sep 26, 2018 12:00 pm

AstraZeneca and MedImmune, its global biologics research and development arm, announced today that the US Food and Drug Administration (FDA) has approved Lumoxiti (moxetumomab pasudotox-tdfk) for the ...

Biotechnology (340)

Active and Sedentary Life Is Determined in Part by Our Genes

Dec 11, 2018 5:00 pm

In one of the most detailed projects of its kind, the scientists studied the activity of 91,105 UK Biobank participants who had previously worn an activity monitor on their wrist for a week. T...

Researchers Were Able to Visualize the Proteasome's Inner Workings

Dec 11, 2018 4:00 pm

LA JOLLA, CA – One of a cell’s most important responsibilities is to break down and recycle proteins that are no longer needed or endanger the cell. This task is carried out by a cellul...

New Immunoassay Technique Measures Extremely Low Concentrations of Small Molecules

Dec 11, 2018 2:00 pm

As medical science has come to understand that the human body is controlled on the molecular level by various proteins, hormones, drugs, and other substances, technologies have developed to detect ...

Cancer (979)

Uncovering the Unique Drug Susceptibility Patterns in Leukemia Cells Could Lead to Appropriate Treatment for AML

Dec 11, 2018 1:00 pm

Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML). Research on ...

The Relationship between DNA Damage and Mutations in Genetic Diseases and Cancer

Dec 11, 2018 12:00 pm

Scientists have reported that many inheritance mutations are caused by DNA damage rather than errors in DNA doubling. The study was conducted by an international research group and published in Nat...

NSD2 Might Be a Therapeutic Target for Metastatic and Resistant Prostate Cancers

Dec 9, 2018 6:00 pm

Cancer Therapy (379)

Uncovering the Unique Drug Susceptibility Patterns in Leukemia Cells Could Lead to Appropriate Treatment for AML

Dec 11, 2018 1:00 pm

Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML). Research on ...

NSD2 Might Be a Therapeutic Target for Metastatic and Resistant Prostate Cancers

Dec 9, 2018 6:00 pm

A New Approach to Cancer Therapeutics by Targeting the Evolution of Cancer Cells

Dec 8, 2018 1:00 pm

Singapore – A team of scientists from Agency for Science, Technology and Research’s (A*STAR) Genome Institute of Singapore (GIS) has identified a new approach to cancer therapeutics by ...

Cardiology (160)

A New Research Reveals Cellular Gene Signatures that Could Be the Key to Understand the Ability of Heart Muscle Repair

Dec 3, 2018 4:00 pm

Repairing heart muscle damaged by a heart attack or other cardiovascular diseases is one of the “holy grails” for cardiovascular scientists. The ability to repair heart muscle – e...

New Research Identifies Two Genes Linked to Tetralogy of Fallot (ToF)

Dec 2, 2018 1:00 pm

Scientists at the University of Manchester have this week published research, funded by the British Heart Foundation (BHF) which shows, for the first time, possible genetic causes of a serious cong...

Is Genetic Predisposition to Alzheimer’s Disease Related to Adiposity and Cardiometabolic Risk Factors Among Children?

Oct 7, 2018 10:00 am

Genetic predisposition to Alzheimer's disease is linked to an increased risk of cardiometabolic disorders already in childhood, a new study from Finland shows. Ongoing at the University of Eastern...

Cell Biology (493)

Researchers Were Able to Visualize the Proteasome's Inner Workings

Dec 11, 2018 4:00 pm

LA JOLLA, CA – One of a cell’s most important responsibilities is to break down and recycle proteins that are no longer needed or endanger the cell. This task is carried out by a cellul...

Newly Identified Phospholipid-Reactive T Cells Could Have Influences on Cancer and Other Diseases

Dec 10, 2018 2:00 pm

Researchers from the UCLA Jonsson Comprehensive Cancer Center and the La Jolla Institute for Immunology have identified a new type of T cell called a phospholipid-reactive T cell that is able to re...

A Computer Model Illustrates the Connection between Physical Organization of DNA and Gene Expression

Dec 10, 2018 12:00 pm

Scientists often try to understand important processes in the cell by interfering and observing what happens. But often the cell just dies. That was the problem that Andrew Spakowitz, associat...

Cell Signaling (133)

Researchers Reveal Why Some Patients’ Immune Systems Can Resist HIV-1

Dec 5, 2018 1:00 pm

Of the 40 million people around the world infected with HIV, less than one per cent have immune systems strong enough to suppress the virus for extended periods of time. These special immune system...

New Insight into How the Immune System Can Be Hampered When it Comes to Fighting Cancer

Dec 4, 2018 2:00 pm

Over the course of evolution, the immune system has developed effective mechanisms to detect pathogens invading the body from outside and to eliminate them before they can cause major damage. Howev...

Using in Vitro Cell Culture Could Contribute to a New Treatment for Schizophrenia

Dec 3, 2018 11:00 am

Belmont, MAA study recently published in Translational Psychiatry, a Nature journal, has shown how using cultured cells from patients with psychotic disorders, such as schizophrenia, to investigate...

Clinical Trials (140)

CAR-T Cell Therapy for Promising Treatment B-cell Lymphoma

Dec 6, 2018 11:00 am

An international phase-2 trial of a CAR-T cell therapy published in the New England Journal of Medicine (and presented at the ASH annual meeting in San Diego)—found that 52 percent of patient...

New Study Provides Evidence that Ibrutinib Is the Most Effective Treatment for Older Adults With Chronic lymphocytic leukemia CLL

Dec 5, 2018 2:00 pm

Results from an multi-institutional, phase 3 clinical trial show that older patients with chronic lymphocytic leukemia (CLL) have a significantly lower rate of disease progression if treated with t...

A New Immunotherapy Can Greatly Extend the Lives of Many People with Advanced Head and Neck Cancer

Dec 3, 2018 12:00 pm

A new immunotherapy can greatly extend the lives of a proportion of people with advanced head and neck cancer, with some living for three years or more, a major new clinical trial reports. Ove...

Dentistry (13)

New Promising Period of Craniofacial Genetics

Jun 27, 2018 11:00 am

Our faces can reveal a lot about us, and now scientists are revealing a lot about faces. PLOS Genetics announces a special collection of papers to highlight recent advances in our understanding of ...

Instead of Filling Cavities, Dentists May Soon Regenerate Teeth

Mar 28, 2018 4:00 pm

For dentists, a cavity is a conundrum—in order to save the tooth they must further damage it. Currently, the primary way to treat a cavity is to excavate the decay and the surrounding area befor...

New Innovative Product To Preserve Oral Health

Dec 7, 2017 12:00 pm

Dentists rely on composite materials to perform restorative procedures, such as filling cavities. Yet these materials, like tooth enamel, can be vulnerable to the growth of plaque, the sticky biofilm ...

Dermatology (36)

New Insight into How the Immune System Can Be Hampered When it Comes to Fighting Cancer

Dec 4, 2018 2:00 pm

Asexual Reproduction Is the Rule for Trichophyton Rubrum

Jul 22, 2018 11:00 am

The sexual habits of Trichophyton rubrum, the fungus that causes athlete’s foot and other kinds of skin and nail infections, were the focus of a study published by Brazilian scientists and inter...

Increased Public's Interest in Melanoma Testing

Jul 17, 2018 10:00 am

TUESDAY, July 10, 2018 (HealthDay News) -- There is moderately high interest in genetic testing for melanoma risk among the general population, according to a study published in the June issue of JAMA...

Developmental Biology (152)

Scientists Apply Karyomapping to Screen for Genetic Merit and Chromosome Disorders in Cattle Embryos

Dec 2, 2018 3:00 pm

The approach, called Karyomapping, was originally designed to detect and screen for single gene and chromosome disorders simultaneously in human IVF embryos. Now the application of the same te...

Scientists Create Synthetic Microorganisms to Study Evolutionary Mysteries

Dec 1, 2018 3:00 pm

Scientists at Scripps Research and their collaborators have created microorganisms that may recapitulate key features of organisms thought to have lived billions of years ago, allowing them to expl...

A New Syndrome Uncovers the First Evidence Linking ODC1 Mutation and Developmental Problems in Humans

Dec 1, 2018 11:00 am

A Michigan State University pediatric researcher and a Spectrum Health physician have identified a new genetic syndrome in a 3-year-old girl who, for more than two years, has gone undiagnosed. ...

Diabetes (116)

Cancer is Associated with an Increased Risk of Diabetes in Cancer Survivors

Sep 22, 2018 12:00 pm

A new retrospective Korean cohort study of more than half a million men and women followed for 10 years shows that a diagnosis of nine types of cancer was associated with a significantly increased ris...

Time-Restricted Feeding May Reverse Diseases Related to Biological Clock Defects

Sep 13, 2018 10:00 am

LA JOLLA—Scientists at the Salk Institute found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic di...

Diabetes and Vitamin D Deficiency

Sep 2, 2018 1:00 pm

Vitamin D is essential for good health. Unlike other vitamins, the main source of vitamin D is from our skin after exposure to sunlight. A mild lack of vitamin D may cause symptoms such as general ach...

Diseases (817)

Using in Vitro Cell Culture Could Contribute to a New Treatment for Schizophrenia

Dec 3, 2018 11:00 am

New Insight into the Role of Immune Checkpoints in Myasthenia Gravis

Dec 3, 2018 10:00 am

Quite literally meaning "grave muscle weakness," myasthenia gravis is a chronic autoimmune disorder that causes serious weakening of skeletal muscles responsible for movements such as ocu...

New Research Identifies Two Genes Linked to Tetralogy of Fallot (ToF)

Dec 2, 2018 1:00 pm

Embryology (11)

The Secret behind Peace Agreement between Foetal Cells and Maternal Immune System

Dec 5, 2018 4:00 pm

The first Human Cell Atlas study of early pregnancy in humans has shown how the function of the maternal immune system is affected by cells from the developing placenta. Rese...

Scientists Produce Mouse Pups from Two Mothers by Using Stem Cells and Gene Editing

Dec 1, 2018 4:00 pm

Researchers at the Chinese Academy of Sciences were able to produce healthy mice with two mothers that went on to have normal offspring of their own. Mice from two dads were also born but only surv...

A New Syndrome Uncovers the First Evidence Linking ODC1 Mutation and Developmental Problems in Humans

Dec 1, 2018 11:00 am

A Michigan State University pediatric researcher and a Spectrum Health physician have identified a new genetic syndrome in a 3-year-old girl who, for more than two years, has gone undiagnosed. ...

Endocrinology (36)

LncRNAs Appear to Be Responsible for Fine Regulation of Genes Involved in Prostate Cancer

Aug 9, 2018 10:00 am

In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone (DHT). For this to happen, these ho...

The Latest Test for Thyroid Nodules

Aug 5, 2018 11:00 am

BOSTON — New data on the latest versions of two top genomic sequencing classifiers (GSC) demonstrate the increasing ability of molecular testing to assist in the management of patients with thyr...

Gestational Oral Low-Dose Estradiol-17β May Affect DNA Methylation in Embryos and Adult Offspring

Jul 5, 2018 11:00 am

The public debate on endocrine disrupting chemicals (EDCs) -- exogenous substances that have the same or similar effects as endogenous hormones -- has been going on for some time. Chemicals such as...

Epigenetics (97)

Scientists Uncover Mechanism Safeguarding Unique Epigenome of Oocytes

Dec 10, 2018 1:00 pm

In mammals, females have a limited supply of oocytes. Oocytes have a unique epigenome with approximately half the DNA methylation of sperm, and the most terminally differentiated somatic cells. Unt...

A Computer Model Illustrates the Connection between Physical Organization of DNA and Gene Expression

Dec 10, 2018 12:00 pm

Scientists often try to understand important processes in the cell by interfering and observing what happens. But often the cell just dies. That was the problem that Andrew Spakowitz, associat...

NSD2 Might Be a Therapeutic Target for Metastatic and Resistant Prostate Cancers

Dec 9, 2018 6:00 pm

Evolution (123)

Discovering PLEKHG6 Gene That Drives Aspects of Brain Development Differently in Primates Compared to Other Species

Dec 11, 2018 3:00 pm

University of Otago researchers have discovered information about a gene that sets primates – great apes and humans – apart from other mammals, through the study of a rare developmental...

Scientists Create Synthetic Microorganisms to Study Evolutionary Mysteries

Dec 1, 2018 3:00 pm

Genes of a Human Origin play a Critical Role in Development of our Large Brains

Sep 23, 2018 12:00 pm

A set of three nearly identical genes found only in humans appear to play a critical role in the development of our large brains, according to a study led by researchers at the University of Califo...

Featured (579)

Discovering PLEKHG6 Gene That Drives Aspects of Brain Development Differently in Primates Compared to Other Species

Dec 11, 2018 3:00 pm

University of Otago researchers have discovered information about a gene that sets primates – great apes and humans – apart from other mammals, through the study of a rare developmental...

New Immunoassay Technique Measures Extremely Low Concentrations of Small Molecules

Dec 11, 2018 2:00 pm

Dna2 Absence Leads to Insertions of DNA Fragments into DNA Breaks

Dec 9, 2018 3:00 pm

Cells have in place a number of mechanisms to protect the integrity of the genome, including processes that repair mistakes that may occur during DNA replication. The enzyme Dna2 participates in DN...

Gastroenterology (65)

Optogenetics Provides a less Toxic Remedy to debilitating gastrointestinal conditions

Sep 10, 2018 11:00 am

A novel light therapy is being investigated as an alternative to prescription drugs to relieve chronic constipation and other intestinal disorders which affect millions of patients around the world. ...

A New Method to Identify Microbial Genes that Make Some Microbes Live in Your Gut

Aug 29, 2018 10:00 am

SAN FRANCISCO, CA—Trillions of tiny microbes and bacteria live in your gut, each with their own set of genes. These gut microbes can have both beneficial and harmful effects on your health, from...

Colon Cancer And The Role Of IGF-1 In Treatment

Jul 28, 2018 2:00 pm

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associate...

Gene Therapy (94)

Removing RCAN1 Gene Might Be A Novel Approach Against Obesity

Dec 6, 2018 11:00 am

It sounds too good to be true, but a novel approach that might allow you to eat as much food as you want without gaining weight could be a reality in the near future. When a single gene known ...

Microparticles Offer a Promising Treatment for Some Blood Disorders

Dec 4, 2018 11:00 am

Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us. Now, a team of University of Delaware resear...

Gene Therapy Leads to "Adaptive Rewiring" in Patients with Parkinson’s Disease

Dec 3, 2018 1:00 pm

A gene therapy treatment for Parkinson’s disease appears to relieve symptoms by rewiring the brain circuits involved in movement. People with Parkinson’s disease have tremors and m...

General (314)

How the Distance of Microbial Competitions Shapes Their Community Structures?

Dec 8, 2018 10:00 am

Inside the microbial communities that populate our world, microbes are fighting for their lives. These tiny organisms are in the soil, in the oceans, and in the human body. Microbes play sever...

A Deeper Insights into Zooplankton Biodiversity

Jul 8, 2018 12:00 pm

Marine zooplankton are tiny animals, roughly the size of insects you might see on a summer day, that drift with ocean currents. Many of them are lovely, but except for scientists who study them, few p...

Genetically Engineered Food Invading Markets !!

Jun 28, 2018 4:30 pm

While there’s currently no evidence that genetically modified organisms harm human health, that isn’t to say there aren’t legitimate reasons to avoid them. Perhaps the most c...

Genetic Diseases (271)

The Relationship between DNA Damage and Mutations in Genetic Diseases and Cancer

Dec 11, 2018 12:00 pm

A New Syndrome Uncovers the First Evidence Linking ODC1 Mutation and Developmental Problems in Humans

Dec 1, 2018 11:00 am

A Michigan State University pediatric researcher and a Spectrum Health physician have identified a new genetic syndrome in a 3-year-old girl who, for more than two years, has gone undiagnosed. ...

Breast Cancer Gene Mutation is not a "Feminine' Issue"

Oct 8, 2018 9:00 am

Cancer is one of the leading causes of death among Americans. At least 10 percent of cancers are caused by inherited mutations in genes such as BRCA1 and BRCA2. Parents with the cancer gene mutatio...

Genetics (1305)

Active and Sedentary Life Is Determined in Part by Our Genes

Dec 11, 2018 5:00 pm

In one of the most detailed projects of its kind, the scientists studied the activity of 91,105 UK Biobank participants who had previously worn an activity monitor on their wrist for a week. T...

Discovering PLEKHG6 Gene That Drives Aspects of Brain Development Differently in Primates Compared to Other Species

Dec 11, 2018 3:00 pm

University of Otago researchers have discovered information about a gene that sets primates – great apes and humans – apart from other mammals, through the study of a rare developmental...

Uncovering the Unique Drug Susceptibility Patterns in Leukemia Cells Could Lead to Appropriate Treatment for AML

Dec 11, 2018 1:00 pm

Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML). Research on ...

Genome & Genomics (334)

XRNAX, A New Method to Look at Protein-RNA Interactions

Dec 9, 2018 5:00 pm

RNA molecules perform vital tasks in every cell: Messenger RNA (mRNA) helps to translate the genetic information stored in the DNA into proteins. However, many other RNA molecules exist, which are ...

Dna2 Absence Leads to Insertions of DNA Fragments into DNA Breaks

Dec 9, 2018 3:00 pm

Scientists Discover a Group of Genes Involved in Regeneration That Are Kept in Different Species

Dec 8, 2018 2:00 pm

Researchers from the Department of Genetics, Microbiology and Statistics and the Institute of Biomedicine of the University of Barcelona (UB), in collaboration with the Centre for Genomic Regulatio...

Gynecology (45)

Only Sequencing Fetal DNA is Enough !!

Aug 11, 2018 12:00 pm

Sequencing the fetal DNA that circulates in a pregnant woman’s blood holds promise for modern genomic medicine, according to a review article by Diana W. Bianchi, M.D., a senior researcher and i...

A Genetic Variation in Progesterone Receptor Might Be Linked to Prematurity Risk

Jun 30, 2018 2:00 pm

Humans have unexpectedly high genetic variation in the receptor for a key pregnancy-maintaining hormone, according to research led by scientists at the Stanford University School of Medicine. The f...

Study Results Shows that a Blood Sample can Estimate Fetal Age and Follow up Growth

Jun 11, 2018 8:00 pm

Measuring RNA fragments in a pregnant woman’s blood gives a reliable estimate of the baby’s due date and can predict if the baby will arrive prematurely, a Stanford-led team has shown. ...

Hematology (103)

Uncovering the Unique Drug Susceptibility Patterns in Leukemia Cells Could Lead to Appropriate Treatment for AML

Dec 11, 2018 1:00 pm

Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML). Research on ...

Scientists Succeed in Turning Human Skin Cells into Blood Stem Cells for the First Time

Dec 8, 2018 12:00 pm

Transplantation of blood stem cells, isolated from mobilized peripheral blood or bone marrow, is a widely utilized therapy for a range of inherited and acquired blood disorders. Allogeneic transpla...

Healthy Blood Stem Cells Seem to Have as Many Mutations as Leukemic Cells!

Dec 2, 2018 11:00 am

Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather the location of th...

Histopathology (11)

A New Enzyme with an Abnormal Amino Acid in its Structure

Jul 14, 2018 12:00 pm

University of Groningen chemists have created a new enzyme with an unnatural amino acid as its active centre. They made the enzyme by modifying an antibiotic binding protein which normally acts as a b...

How Oncogenic Mutant Cells Lead The War Against Normal Ones To Expand Its Property in Tissue?

Jun 24, 2018 11:00 am

Cells in multicellular tissues adhere to each other. Epithelial tissues on the surface layer of the intestines and skin pack cells into a hexagonal (honeycomb) pattern, with cells adhering tightly ...

Surprising Discoveries Limit the Importance of Apoptosis in Embryonic Development

May 23, 2018 10:00 am

Australian researchers have made a surprise discovery that could rewrite our understanding of the role programmed cell death plays in embryonic development and congenital birth defects. The team sh...

Immunology (407)

“Block and Lock” Strategy to Control HIV Latency through Manipulation of Tat Gene Circuit

Dec 10, 2018 4:00 pm

A new study suggests that a genetic switch that causes latent HIV inside cells to begin to replicate can be manipulated to completely eradicate the virus from the human body. Cells harboring latent...

Newly Identified Phospholipid-Reactive T Cells Could Have Influences on Cancer and Other Diseases

Dec 10, 2018 2:00 pm

The Role of CLIP-170, a Microtubule-binding Protein in T Cell Activation

Dec 9, 2018 1:00 pm

When bacteria or viruses enter the body, proteins on their surfaces are recognized and processed to activate T cells, white blood cells with critical roles in fighting infections. During T-cell act...

Infectious Diseases (136)

Researchers Reveal Why Some Patients’ Immune Systems Can Resist HIV-1

Dec 5, 2018 1:00 pm

How Could HIV DNA Be Blocked from Entering the Cell Nucleus?

Dec 4, 2018 1:00 pm

Multiple components of the nuclear pore complex and nuclear import machinery enable a protein called human myxovirus resistance 2 (MX2) to inhibit HIV-1 infection, according to a study published No...

Synthetic DNA-delivered Antibodies Protect Against Ebola in Preclinical Studies

Dec 1, 2018 5:00 pm

Scientists at The Wistar Institute and collaborators have successfully engineered novel DNA-encoded monoclonal antibodies (DMAbs) targeting Zaire Ebolavirus that were effective in preclinical model...

Infertility (34)

Scientists Uncover Mechanism Safeguarding Unique Epigenome of Oocytes

Dec 10, 2018 1:00 pm

Gens And Its Role In Fertility

Aug 7, 2018 10:00 am

When Joan Jorgensen was an undergraduate at the University of Wisconsin-Madison, her roommate confided that she had just one period before going through menopause in high school. Doctors told Jorgense...

Discovering a Protein that Organizes the Assembly of the Zygotic Genome at Fertilization

Aug 4, 2018 11:00 am

A research team from the Center for Biomedical Research (CBMR), at the University of Algarve (UAlg), and Instituto Gulbenkian de Ciência (IGC), led by Rui Gonçalo Martinho (UAlg) and P...

Microbiology (202)

How the Distance of Microbial Competitions Shapes Their Community Structures?

Dec 8, 2018 10:00 am

Inside the microbial communities that populate our world, microbes are fighting for their lives. These tiny organisms are in the soil, in the oceans, and in the human body. Microbes play sever...

Creating Microbes with an Expanded Genetic Code Can Open Up New Avenues in Synthetic Biology and Protein Engineering

Dec 3, 2018 2:00 pm

New Approach Identifies More Than 6,000 Antibiotic Resistance Genes in Gut Bacteria

Dec 2, 2018 12:00 pm

Molecular Biochemistry (495)

New Immunoassay Technique Measures Extremely Low Concentrations of Small Molecules

Dec 11, 2018 2:00 pm

Chemists Develop Highly Precise Synthetic Polymers of Multi-function

Dec 10, 2018 3:00 pm

Researchers at Imperial College London have developed a new class of multi-functional sequence-defined polymers. A team of chemical engineers and chemists in the Livingston Group have used liq...

Newly Identified Phospholipid-Reactive T Cells Could Have Influences on Cancer and Other Diseases

Dec 10, 2018 2:00 pm

Molecular Pharmacology (163)

Stearoyl CoA Desaturase Enzyme as a Target for Parkinson Treatment

Dec 6, 2018 12:00 pm

The human brain is rich in lipids. Investigators studying Parkinson's disease (PD) have become increasingly interested in lipids since both molecular and genetic studies have pointed to the dis...

Could HPV Be Treated by A Cancer Drug?

Dec 4, 2018 10:00 am

Preclinical experiments by University of Alabama at Birmingham researchers suggest the cancer drugs vorinostat, belinostat and panobinostat might be repurposed to treat infections caused by human p...

New Study Showed Discovered small molecules Which Are Targeting A Specific Protein in Autoinflammatory Diseases

Jul 21, 2018 9:00 am

EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory ...

Mycology (8)

Asexual Reproduction Is the Rule for Trichophyton Rubrum

Jul 22, 2018 11:00 am

The sexual habits of Trichophyton rubrum, the fungus that causes athlete’s foot and other kinds of skin and nail infections, were the focus of a study published by Brazilian scientists and inter...

Identification of the Biosynthetic Gene Cluster for Highly Oxygenated Steroids Group Derived from Fungi

Jun 24, 2018 6:00 pm

A group of researchers from Graduate School of Pharmaceutical Sciences at The University of Tokyo and Institute of Traditional Chinese Medicine and Natural Products at Jinan University, identified ...

Fungal Cells Use Surprising Method To Communicate With Each Other!

May 1, 2018 1:00 pm

The idea of microbes joining forces inside your body to wreak havoc and cause disease sounds frightening — and it should. Now, scientists have found that a particular type of fungus does just th...

Nanotechnology (56)

Based on the HIV Envelope Protein, Scientists Unveil Promising New HIV Vaccine Strategy

Dec 2, 2018 4:00 pm

The new vaccine strategy, described in a paper on November 23 in Science Advances, is based on the HIV envelope protein, Env. This complex, shape-shifting molecule has been notoriously difficult to...

The Advance in the DNA Nanotechnology Field

Sep 26, 2018 12:00 pm

In the journal Nature Communications, Carlos Castro and Ratnasingham Sooryakumar and their colleagues from The Ohio State University report that the control system reduced the response time of prototy...

A synthetic DNA Enzyme Flips Lipids Causing Cancer Cell Death

Jul 10, 2018 10:00 am

A new synthetic enzyme, crafted from DNA rather than protein, flips lipid molecules within the cell membrane, triggering a signal pathway that could be harnessed to induce cell death in cancer cells. ...

Neurology (667)

Discovering PLEKHG6 Gene That Drives Aspects of Brain Development Differently in Primates Compared to Other Species

Dec 11, 2018 3:00 pm

University of Otago researchers have discovered information about a gene that sets primates – great apes and humans – apart from other mammals, through the study of a rare developmental...

The Influence of Microglial Elimination on Preventing Hyper Immune Sensitivity after Stress

Dec 6, 2018 1:00 pm

Using an animal model of chronic stress, researchers at The Ohio State University have shown that the immune cells of the brain, called microglia, hold unique signatures of chronic stress that leav...

Stearoyl CoA Desaturase Enzyme as a Target for Parkinson Treatment

Dec 6, 2018 12:00 pm

The human brain is rich in lipids. Investigators studying Parkinson's disease (PD) have become increasingly interested in lipids since both molecular and genetic studies have pointed to the dis...

Nutrition (124)

Time-Restricted Feeding May Reverse Diseases Related to Biological Clock Defects

Sep 13, 2018 10:00 am

LA JOLLA—Scientists at the Salk Institute found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic di...

Extra Carbon Dioxide is Making some of the most Important Crops Less Nutritious by changing their Chemical Makeup !!

Aug 28, 2018 1:00 pm

WASHINGTON — When scientists want to figure out how climate change might disrupt the world’s food supplies, they often explore how rising temperatures could shift growing seasons or how mo...

A New Scientific Advisory from the American Heart Association (AHA)

Aug 28, 2018 12:00 pm

In an updated scientific advisory, the American Heart Association (AHA) reaffirms advice that adults consume fish two times per week to help reduce the risk for congestive heart failure, coronary hear...

Obesity (101)

Removing RCAN1 Gene Might Be A Novel Approach Against Obesity

Dec 6, 2018 11:00 am

It sounds too good to be true, but a novel approach that might allow you to eat as much food as you want without gaining weight could be a reality in the near future. When a single gene known ...

The Largest Genetic Study of Varicose Veins Provide a New Evidence for the Condition

Oct 1, 2018 10:00 am

The taller you are, the more likely you are to develop varicose veins, according to a study led by Stanford University School of Medicine researchers that examined the genes of more than 400,000 peopl...

Time-Restricted Feeding May Reverse Diseases Related to Biological Clock Defects

Sep 13, 2018 10:00 am

LA JOLLA—Scientists at the Salk Institute found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic di...

Ophthalmology (40)

Identifying Subtypes of Retinal Ganglion Cells by Single-Cell RNA Sequencing Technologies

Jul 28, 2018 1:00 pm

Single-cell sequencing technologies are filling in fine details in the catalog of life. Researchers at the University of Connecticut Health Center (UConn Health) and The Jackson Laboratory (JAX) ha...

A Genetic Mutation Associated with Neuromyelitis Optica (NMO)

Jun 28, 2018 12:00 pm

Scientists conducting one of the largest full DNA analyses of a rare disease have identified a gene mutation associated with a perplexing brain condition that blinds and paralyzes patients. A ...

The Largest-Ever Genetic Study Identified 161 Genetic Factors for Myopia

Jun 27, 2018 7:00 pm

The international Consortium for Refractive Error and Myopia (CREAM) recently published the largest-ever genetic study of myopia in Nature Genetics. Researchers from the Gutenberg Health Study at t...

Organizations / Institutions (147)

Agilent's New Chemical Imaging System Represents a Breakthrough in Both Chemical Imaging and Spectral Analysis

Dec 1, 2018 12:00 pm

Agilent Technologies Inc. (NYSE: A) today introduced a new approach to chemical imaging that will bring greater clarity and unprecedented speed to pharmaceutical, biomedical, food, and materials sc...

Merck’s Paired CRISPR Nickases Technique can Help us to Correct Genetic Defects in Gene Therapy Patients

Sep 27, 2018 10:00 am

Darmstadt, Germany, August 15, 2018 – Merck, the vibrant science and technology company, today announced that the Australian Patent Office has allowed the company’s patent application for ...

Alecensa® is a New Roche's Drug as an Initial Treatment for ALK

Sep 23, 2018 10:00 am

Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the China National Drug Administration (CNDA) has granted marketing authorisation for Alecensa® (alectinib) as a monotherapy treatment for p...

Osteology (23)

A Malfunctioning Gene May Associated with Ankylosing Spondylitis

Sep 4, 2018 11:00 am

New Drugs from FDA for Osteoarthritis Pain and Hypertension

Jun 28, 2018 5:30 pm

The US Food and Drug Administration (FDA) approved a combination of amlodipine besylate and the nonsteroidal anti-inflammatory drug (NSAID) celecoxib (Consensi, Kitov Pharma) for individuals with o...

Spinal Stimulation Helps Paralyzed Patients Regain Function

May 5, 2018 10:00 am

Once a person has suffered a spinal cord injury, there isn't much to be done except to learn how to live with paralysis and loss of function. That could change, thanks to the work of a team of sci...

Otolaryngology (4)

New Technique That Will Force The Centromere To Give Up Its Secrets

Dec 11, 2017 3:00 pm

A new technique may force the centromere -- the mysterious stretch of DNA in the center of every chromosome -- to give up its secrets at last. The first test of the approach has yielded clues about th...

How Sleep Apnea Can Be a Risk Factor for Diabetes?

Sep 19, 2017 10:00 am

Sleep apnea, left untreated for even a few days, can increase blood sugar and fat levels, stress hormones and blood pressure, according to a new study of sleeping subjects. This research adds further ...

Sensory cell regeneration, the new path in treating hearing loss.

May 20, 2017 2:00 pm

In an apparent first, St. Jude Children's Research Hospital investigators have used genetic manipulation to regenerate auditory hair cells in adult mice. The research marks a possible advance in t...

Parasitology (43)

Bone Marrow is a Major Reservoir for P. Vivax Malaria Parasite

Jul 9, 2018 2:00 pm

NEW YORK (Reuters Health) - Beyond blood, bone marrow is a major reservoir of the malaria parasite Plasmodium vivax, according to an international group of researchers. As Dr. Matthias Marti told R...

Two Proteins Recognize and Translate DNA Methylation Marks in Schistosoma Mansoni

Jul 5, 2018 1:00 pm

Two proteins that recognize and translate DNA methylation marks in Schistosoma mansoni are required for growth of adult stem cells in the parasitic flatworm, as well as production of eggs, accordin...

Revealing for the First Time the Evolutionary Path of Plasmodium falciparum !!

Jun 24, 2018 7:00 pm

The evolutionary path of the deadliest human malaria parasite, Plasmodium falciparum, has been revealed for the first time. This parasite is a member of a parasite family called the Laverania that ...

Pediatrics (85)

Healthy Blood Stem Cells Seem to Have as Many Mutations as Leukemic Cells!

Dec 2, 2018 11:00 am

Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather the location of th...

A New Syndrome Uncovers the First Evidence Linking ODC1 Mutation and Developmental Problems in Humans

Dec 1, 2018 11:00 am

A Michigan State University pediatric researcher and a Spectrum Health physician have identified a new genetic syndrome in a 3-year-old girl who, for more than two years, has gone undiagnosed. ...

Parents should Pay Attention to the Food that they Give to their hereditary fructose intolerance (HFI) Babies

Sep 25, 2018 1:00 pm

Babies with inherited intolerance of fructose face a risk of acute liver failure if they are fed certain widely available formulas containing fructose, pediatricians and geneticists are warning. Ba...

Pharmacogenetics (26)

A New Approach to Cancer Therapeutics by Targeting the Evolution of Cancer Cells

Dec 8, 2018 1:00 pm

Singapore – A team of scientists from Agency for Science, Technology and Research’s (A*STAR) Genome Institute of Singapore (GIS) has identified a new approach to cancer therapeutics by ...

A New Syndrome Uncovers the First Evidence Linking ODC1 Mutation and Developmental Problems in Humans

Dec 1, 2018 11:00 am

A Michigan State University pediatric researcher and a Spectrum Health physician have identified a new genetic syndrome in a 3-year-old girl who, for more than two years, has gone undiagnosed. ...

Lumoxiti, the First New Treatment Option for HCL's Patients in Over 20 Years

Sep 26, 2018 12:00 pm

Physiology (28)

Parents should Pay Attention to the Food that they Give to their hereditary fructose intolerance (HFI) Babies

Sep 25, 2018 1:00 pm

Understanding the Effects of Aging on Mitochondria

Sep 16, 2018 11:00 am

Defective energy production in old neurons might explain why our brains are so prone to age-related diseases. Salk researchers used a new method to discover that cells from older individuals had impai...

Time-Restricted Feeding May Reverse Diseases Related to Biological Clock Defects

Sep 13, 2018 10:00 am

LA JOLLA—Scientists at the Salk Institute found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic di...

Products & Technologies (589)

New Immunoassay Technique Measures Extremely Low Concentrations of Small Molecules

Dec 11, 2018 2:00 pm

Agilent's New Chemical Imaging System Represents a Breakthrough in Both Chemical Imaging and Spectral Analysis

Dec 1, 2018 12:00 pm

AstraZeneca provides Update on GALATHEA Phase III Trial for Fasenra in Chronic Obstructive Pulmonary Disease

Oct 10, 2018 9:00 am

Proteome & Proteomics (34)

A New Research Reveals Cellular Gene Signatures that Could Be the Key to Understand the Ability of Heart Muscle Repair

Dec 3, 2018 4:00 pm

Repairing heart muscle damaged by a heart attack or other cardiovascular diseases is one of the “holy grails” for cardiovascular scientists. The ability to repair heart muscle – e...

The New Switch And Its Biological Uses

Oct 6, 2018 12:00 pm

A biological switch that reliably turns protein expression on at will has been invented by University of Bath and Cardiff University scientists. The switch enables control of genome editing tools that...

Cells know how to Prepare Supplies Needed for Division !!

Sep 24, 2018 12:00 pm

How does a cell know when to divide? We know that hundreds of genes contribute to a wave of activity linked to cell division, but to generate that wave new research shows that cells must first grow...

Psychology (113)

The Influence of Microglial Elimination on Preventing Hyper Immune Sensitivity after Stress

Dec 6, 2018 1:00 pm

Does Your Environment Determine the Result of Your IQ?

Oct 2, 2018 10:00 am

Is there a link between differences in IQ test performance and the activity of certain genes? Researchers from Charité – Universitätsmedizin Berlin have shown that modifications in t...

Dopamine Neurons And Theire Roles In Diseases

Sep 30, 2018 9:00 am

Dopamine neurons are located in the midbrain, but their tendril-like axons can branch far into the higher cortical areas, influencing how we move and how we feel. New genetic evidence has revealed tha...

Pulmonary & Respiratory Medicine (36)

A Novel New Way to Treat Asthma

Sep 16, 2018 12:00 pm

An invisible particle enters your lungs. The next thing you know breathing becomes difficult. You are having as asthma attack. Asthma is one of the most common and difficult to endure chronic conditio...

Researchers Have Identified a Genetic Bio-markers to Test Asthma Simply & Accurately

Jun 20, 2018 8:00 pm

Mount Sinai researchers have identified a genetic biomarker of asthma that can be tested for using a simple nasal brush and basic follow-up data analysis. This inexpensive diagnostic test can accur...

Study Identifies New Molecular Target For Treating The Deadly Lung Disease "IPF"

May 2, 2018 12:00 pm

Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclini...

Regenerative Medicine & Cell Therapy (47)

Scientists Discover a Group of Genes Involved in Regeneration That Are Kept in Different Species

Dec 8, 2018 2:00 pm

Scientists Succeed in Turning Human Skin Cells into Blood Stem Cells for the First Time

Dec 8, 2018 12:00 pm

Could We Maintain the Unlimited Potential of Stem Cells? A Protein Complex "BAF" Has the Answer!

Dec 6, 2018 2:00 pm

Embryonic stem cells (ESCs) are the very definition of being full of potential, given that they can become any type of cell in the body. Once they start down any particular path toward a type of ti...

Scientists (7)

Dr. Amin Arnaout Recipient of The Prestigious Homer W. Smith Award

May 15, 2018 9:00 am

Dr. Amin Arnaout has been honored by the American Society of Nephrology (ASN) as recipient of the 2018 Homer W. Smith Award and recognized as “an individual who has made outstanding contribut...

Dr. Al-Zayani Receives The Venus Medical Award at a Ceremony In India

May 2, 2018 2:00 pm

Dr. Salman Hamad Al-Zayani, the Assistant Professor of Public Health at the College of Medicine and Medical Sciences at the Arabian Gulf University (AGU), has received the Venus International Medical ...

The Brain Prize This Year Goes To Alzheimer's Researchers

Mar 11, 2018 9:00 am

Four dementia scientists have shared this year's 1m Euro brain prize for pivotal work that has changed our understanding of Alzheimer's disease. Profs John Hardy, Bart De Strooper, Michel G...

Single Nucleotide Polymorphisms (13)

Low Genetic Diversity Put the Singapore Freshwater Crab Under the Threat of Extinction

Jun 24, 2018 4:00 pm

Researchers from NUS and National Parks Board (NParks) have established that the critically endangered Singapore freshwater crab (Johora singaporensis) does not mix or breed between different popul...

Mendelian Randomization Analysis to More Precision and Less Time and Cost

Jun 7, 2018 1:00 pm

The evolution of medicine relies heavily on the results of clinical trials, which while essential, are extremely costly and carry the potential of unintended adverse consequences. Now researchers from...

Mutations Other Than BRCA Can Cause Second Primary Breast Cancer

Jun 6, 2018 5:00 pm

Rates of inherited mutations in genes other than BRCA1/2 are twice as high in breast cancer patients who have had a second primary cancer—including, in some cases, different types of breast c...

Stem Cells & Cancer Stem Cells (203)

Uncovering the Unique Drug Susceptibility Patterns in Leukemia Cells Could Lead to Appropriate Treatment for AML

Dec 11, 2018 1:00 pm

Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML). Research on ...

Scientists Succeed in Turning Human Skin Cells into Blood Stem Cells for the First Time

Dec 8, 2018 12:00 pm

Could We Maintain the Unlimited Potential of Stem Cells? A Protein Complex "BAF" Has the Answer!

Dec 6, 2018 2:00 pm

Toxicology (34)

How the Distance of Microbial Competitions Shapes Their Community Structures?

Dec 8, 2018 10:00 am

Inside the microbial communities that populate our world, microbes are fighting for their lives. These tiny organisms are in the soil, in the oceans, and in the human body. Microbes play sever...

Impacts of highly Hazardous Pollutants Dioxins on Plants

Sep 9, 2018 11:00 am

Dioxins are highly hazardous pollutants that have well characterized impacts on both animal and human health. However, the biological effects of dioxins on plants have yet to be described in detail. ...

Prenatal Exposure to the DDT Toxin may be Related to Autism

Sep 4, 2018 10:00 am

National birth cohort study finds DDT metabolites in the blood of pregnant women are associated with elevated odds of autism in offspring. A study of more than 1 million pregnancies in Finland...

Transcriptome & Transcriptomics (10)

Scientists Discover a Group of Genes Involved in Regeneration That Are Kept in Different Species

Dec 8, 2018 2:00 pm

A New Approach to Cancer Therapeutics by Targeting the Evolution of Cancer Cells

Dec 8, 2018 1:00 pm

Singapore – A team of scientists from Agency for Science, Technology and Research’s (A*STAR) Genome Institute of Singapore (GIS) has identified a new approach to cancer therapeutics by ...

A New Research Reveals Cellular Gene Signatures that Could Be the Key to Understand the Ability of Heart Muscle Repair

Dec 3, 2018 4:00 pm

Repairing heart muscle damaged by a heart attack or other cardiovascular diseases is one of the “holy grails” for cardiovascular scientists. The ability to repair heart muscle – e...

Urology (11)

Genetic Mutations Could Play a Vital Role in Improving Diagnosis of Prostate Cancer Patients

Sep 17, 2018 10:00 am

Scientists have discovered a link between certain genetic mutations, the aggressiveness of prostate cancer, risk of developing the disease and poorer survival rates of patients. The gene, called ANO7,...

Disabled Kidney Function May Cause Diabetes

Dec 16, 2017 4:00 pm

Diabetes is known to increase a person's risk of kidney disease. Now, a new study from Washington University School of Medicine in St. Louis suggests that the converse also is true: Kidney dysfunc...

Rare resistance mutation reduces treatment choices for urinary tract infections

Sep 9, 2017 6:00 pm

Nearly 20 percent of women aged 15-29 are diagnosed with a urinary tract infection (UTI). Now, investigators have uncovered a rare mutation that renders a UTI-causing pathogen resistant to levofloxaci...

Vaccines (53)

Based on the HIV Envelope Protein, Scientists Unveil Promising New HIV Vaccine Strategy

Dec 2, 2018 4:00 pm

Novel Approach Has the Potential to Measure the Effectiveness of Bexsero More Accurately

Jun 21, 2018 1:00 pm

Researchers at Leicester and the Meningococcal Reference Unit have developed a new approach to assess the effectiveness of the Men B vaccine, Bexsero®, against different strains that cause meni...

Why Does the Flu Vaccine Work for Some, and Not Other, Genetically Speaking?

May 30, 2018 10:00 am

Each year, 132 million Americans flock to doctors’ offices, pharmacies, and clinics for flu shots. With the onset of “flu season” each year, 41% of the population opts to get ...

Virology (195)

“Block and Lock” Strategy to Control HIV Latency through Manipulation of Tat Gene Circuit

Dec 10, 2018 4:00 pm

The Role of Cellular Protein CK1-alpha in the Replication of Rotavirus

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Rotaviruses, like all viruses, reproduce inside living cells. Making new viruses requires assembling replication factories via a complex, little known process that involves both viral and cellular ...

Researchers Reveal Why Some Patients’ Immune Systems Can Resist HIV-1

Dec 5, 2018 1:00 pm

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New Immunoassay Technique Measures Extremely Low Concentrations of Small Molecules

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Removing RCAN1 Gene Might Be A Novel Approach Against Obesity

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