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Researchers Develop a New Method to Analyze Genomic Changes Associated With Cancer
A new method for analyzing the scrambled genomes of cancer cells gives researchers for the first time the ability to simultaneously identify two different types of genetic changes associated with canc... Read More
Researchers Identify Cancer Gene Mutations and Corresponding Drug Combinations
In an effort to expand the number of cancer gene mutations that can be specifically targeted with personalized therapies, researchers at University of California San Diego School of Medicine and Moore... Read More
Researchers Develop a New Imaging Technique to Detect Androgen Receptors on Prostate Cancer Cells
Prostate cancer is one of the most common cancers in men. Tumor growth is critically regulated by the androgen receptor, and treatment strategies to lower androgens, such as testosterone, are a mainst... Read More
Researchers Identify a Gene Mutation Implicated in Intellectual Disability Disorder
Scientists at the Wellcome Trust Sanger Institute and Max Planck Institute for Psycholinguistics have found a gene responsible for an intellectual disability disorder and proven how it works. The rese... Read More
Paternal Obesity Can Affect Not only Health of Children, But Also Grandchildren
With more than 14 million Australians now overweight or obese, researchers are warning of the harmful legacy that parental obesity can have on future generations. It follows a vital breakthrough in ob... Read More
Researchers Identify Genetic Mutations Responsible for a Rare Aortic Disease
A new finding by clinicians and geneticists may solve a medical mystery that one family has faced for the last 15 years and help identify the cause of a rare aortic disease in other patients as well. ... Read More
Stem Cells
Researchers Discover a New Pathway for Regeneration of Damaged Muscle Tissue
A key gene enables the repair of injured muscle throughout life. This is the finding of a study in mice led by researchers at NYU Langone Medical Center and the University of Colorado at Boulder, and ... Read More
Researchers Discover a New Micro-RNA Controls Self Renewal Process of Stem Cells
International stem cell scientists, co-led in Canada by Dr. John Dick and in the Netherlands by Dr. Gerald de Haan, have discovered the switch to harness the power of cord blood and potentially increa... Read More
Researcher Identify Chemical and Biological Signals Necessary to Quickly Produce 12 Cells Types from Stem Cells
Researchers at the Stanford University School of Medicine have mapped out the sets of biological and chemical signals necessary to quickly and efficiently direct human embryonic stem cells to become p... Read More
Researchers Discover Metabolic Pathways Required by Mucorales fungi to Infect Patients
Research published today in the journal, Nature Communications, provides new insights into the evolution of Mucorales fungi, which cause a fatal infection in ever-increasing segments of patient popula... Read More
Researchers Discover That Master Beta Cells in Pancreas Controls Response to Glucose
The significant role of beta cell 'hubs' in the pancreas has been demonstrated for the first time, suggesting that diabetes may due to the failure of a privileged few cells, rather than the be... Read More
Researchers Reveal That Sitting for Long Periods May Increase Risk of Cardiovascular Disease
A team of researchers affiliated with several institutions in the U.S. has discovered what they claim is the maximum amount of time a person can sit on average per day before it starts to damage their... Read More
Inhibition of an Immune Molecule Prevents Obesity in Mice
Obesity can cause a variety of health complications in affected individuals. Several lines of evidence support an association between chronic inflammation in adipose tissue and obesity complications. ... Read More
Researchers Reveal Mechanism by Which Plants Produce a Whole Set of Medicinal Compounds
Scientists at the John Innes Centre have discovered a key "twist" in a Rubik's cube-like plant puzzle, which could pave the way to new, or more effective pharmaceuticals. Several member... Read More
Researchers Develop a New Faster Method to Model Protein - Protein Interactions
Protein-protein interactions (PPIs) are the basis of cellular functions, and when these processes are compromised diseases such as cancer emerge. For years scientists have tried with mixed success to ... Read More
Shutting off Certain Brain Region to Study Its Functions
Capitalizing on experimental genetic techniques, researchers at the California National Primate Research Center, or CNPRC, at the University of California, Davis, have demonstrated that temporarily tu... Read More
Researchers Study Unusual Mechanism of Action of an Anti-HIV Drug
A new type of HIV drug currently being tested works in an unusual way, scientists in the Molecular Medicine Partnership Unit, a collaboration between EMBL and Heidelberg University Hospital, have foun... Read More
Researcher Develop a New Technique to Treat Diseases Caused by a Mutation in a Bicistronic Gene
Neuroscientists at the University of Chicago studying a unique gene that expresses two proteins, one that is necessary for life and another, that when mutated causes a neurodegenerative disease called... Read More
Cellular Recycling Mechanisms Converge Inside One Organelle
Autophagy (literally "eating of self") is one of the most important process by which cells renew themselves and eliminate components no longer functional. In short, they recycle. The curren... Read More
Researchers Discover Additional Wall Surrounds Chloroplasts in Moss
Researchers of Kumamoto University in Japan have succeeded in the world's first visualization of a peptidoglycan 'wall' present in the chloroplasts of bryophytes (moss plants). Until now, ... Read More
Researcher Study Effects of Dietary Restriction on Longevity
Dietary restriction, or limited food intake without malnutrition, has beneficial effects on longevity in many species, including humans. A new study from the Sanford Burnham Prebys Medical Discovery I... Read More
Saliva DNA Preservation Devices Used in "Detection of Novel Integrons in the Metagenome of Human Saliva"
Integrons are commonly found in bacterial genomes, especially in most Gram-negative bacteria. They are involved in the dissemination and differential expression of genes in the bacterial popula... Read More
New technique Developed to Deliver Chemotherapeutics to Brain Tumors
Great discoveries do come in small packages. Few know that better than Ann-Marie Broome, Ph.D., who feels nanotechnology holds the future of medicine with its ability to deliver powerful drugs in tiny... Read More
Camouflaged Trojan Horses Engineered to Specifically Target Inflammation
Nanosized Trojan horses created from a patient's own immune cells have successfully treated inflammation by overcoming the body's complex defense mechanisms, perhaps leading to broader applica... Read More
Nanoparticle Dendrimer Carriers Designed to Deliver microRNA Tumor Supressors to Liver Cancer
University of Texas Southwestern Medical Center chemists have successfully used synthetic nanoparticles to deliver tumor-suppressing therapies to diseased livers with cancer, an important hu... Read More
Distinct microRNA Fingerprint Helps Diagnose Germ Cell Tumours
A non-invasive, low cost blood test that could help doctors diagnose some types of malignant childhood tumour has been developed by researchers at the University of Cambridge and Addenb... Read More
MicroRNA Expression in Heart Activates Cardiomyocyte Cell Proliferation after Heart Attacks
The heart tissue of mammals has limited capacity to regenerate after an injury such as a heart attack, in part due to the inability to reactivate a cardiac muscle cell and proliferation program. Recen... Read More
Low Level of Cell Senescence MicroRNA Reported in Most Pancreatic Cancers
Pancreatic cancer carries a very bleak prognosis for patients. However, a recent breakthrough by two research teams, including one at the Hôpital Maisonneuve-Rosemont (CIUSSS-EST, Mont... Read More
Researchers Discover That Liver - Not the Spleen is the Major Site of Red Blood Cells Recycling
What happens when red blood cells become damaged or reach the end of their normal life span, and how is the iron required for carrying oxygen recycled? A new study led by Massachusetts General Hospita... Read More
Researchers Warns of Harmful Side Effects of Antioxidants
The lay press and thousands of nutritional products warn of oxygen radicals or oxidative stress and suggest taking so-called antioxidants to prevent or cure disease. Professor Pietro Ghezzi at the Bri... Read More
Researchers Discover a New Protein Impairs Insulin Signaling
Medication can help trigger the enzyme that kick starts insulin production in the body, but the drugs don't always work for those who are obese or diabetic, and most need to regulate their glucose... Read More
Researchers Report New Mechanisms by Which Advanced Melanoma Resist Immunotherapy
UCLA researchers have identified mechanisms that determine how advanced melanoma can become resistant to immune checkpoint inhibitors, a discovery that could lead to the development of new and improve... Read More
Researchers Identify a Gene Implicated in Poor Immune Response Against Fungal Infection
Fungal infections pose a major threat to hospital patients and have proven difficult to combat, but scientists have unlocked evidence that could lead to more effective treatment. Researchers at The O... Read More
Genetics Impart Resistance Against Flu Virus Infections in Certain Bird Species
The genes of some chickens make them almost completely resistant to a serious strain of bird flu, new research has revealed. The findings, which are published in the journal Scientific Reports, show ... Read More
Alzheimer's Disease
Antibiotics May Help Eliminating Amyloid Beta Plaques in Patients With Alzheimer
Long-term treatment with broad spectrum antibiotics decreased levels of amyloid plaques, a hallmark of Alzheimer's disease, and activated inflammatory microglial cells in the brains of mice in a n... Read More
New Study Reveals Mechanism of How TREM2 Gene Variation Cause Alzheimer Disease
People with a variant copy of the TREM2 gene have an increased risk of developing Alzheimer's disease, but researchers are only beginning to understand why. A Genentech study has uncovered detail... Read More
Researchers Reveal a Mechanism by Which Alzheimer Disease Spread Through Brain Regions
A toxic Alzheimer's protein can spread through the brain—jumping from one neuron to another—via the extracellular space that surrounds the brain's neurons, suggests new research fr... Read More
Neurodegenerative Diseases
Researchers Develop a New Imaging Technique to Quantify Functional Brain Synapsis
A Yale-led team of researchers developed a new approach to scanning the brain for changes in synapses that are associated with common brain disorders. The technique may provide insights into the diagn... Read More
Researchers Develop a New Drug That Treats Huntington Disease by Two Separate Mechanisms
A major, multi-institutional study based at Massachusetts General Hospital (MGH) has identified a promising treatment strategy for Huntington's disease (HD). In their report receiving online publi... Read More
A New Drug Protects From Neural Cell Death After Mild Traumatic Brain Injury
Whether at school, in car accidents, on the sports field or the battlefield, mild traumatic brain injury (mTBI) is a common part of our lives. It is especially frequent among children, athletes, and t... Read More

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