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Aging (85)
Genoms And Its Roles In Biological Ageing
Sep 29, 2018 10:00 am

Senescence, or biological ageing, refers to the general deterioration of an organism's physiological functions, leading to increased susceptibility to diseases and ultimately death. It is a comple...
The Relationship Between Sex Hormones and Cardiovascular Disease in Post- Menopausal Women
Jul 10, 2018 2:00 pm

In post-menopausal women, having a higher blood level of a male hormone (testosterone) and a higher ratio of the male-type to-female type (estrogen) of hormones is associated with a higher risk of ...
The Secret of Long, Healthy and Cancer free Life of Bats
Jun 28, 2018 4:00 pm

Bats are some of the longest-lived mammals in the world relative to their size. Professor Emma Teeling and her team studied bat telomeres, the caps at the end of chromosomes, in search of longevity...
More
Arthrology (6)
Neandertal Genes Shed Light on Endocranial Globularity of Modern Humans
Dec 17, 2018 6:00 pm

A characteristic feature of modern humans is the unusually round skull and brain, in contrast to the elongated shape seen in other human species. By studying Neandertal DNA fragments found in the g...
A Malfunctioning Gene May Associated with Ankylosing Spondylitis
Sep 4, 2018 11:00 am

A new Michigan State University study has found that a malfunctioning gene associated with a common arthritic disease that often starts in teenagers is now directly linked to the loss of vital immu...
a World With NO Arthritis
Feb 15, 2018 12:00 pm

There may come a time when people won’t require surgery to replace their joints. One researcher, Denis Evseenko, MD, Ph.D., a scientist at Keck School of Medicine at the University of Southern C...
More
Bacteriology (265)
Researchers Develop A High-Throughput RNA Sequencing Strategy to Study the Activity of the Gut Microbiome
Dec 18, 2018 3:00 pm

Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome. The new tools analyze transfer RNA (tRNA), a mo...
Scientists Discover a Set of Simple Rules That Determine the Precision of CRISPR/Cas9 Genome Editing in Human Cells
Dec 18, 2018 11:00 am

Crick scientists have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells. These rules, published in Molecular Cell, could help to improve the...
Researchers Took an Important Step toward the Goal of Making Diseased Hearts Heal Themselves
Dec 17, 2018 12:00 pm

A team of Rutgers scientists, including Leonard Lee and Shaohua Li, have taken an important step toward the goal of making diseased hearts heal themselves – a new model that would reduce the ...
More
Bioinformatics (214)
Researchers Develop A High-Throughput RNA Sequencing Strategy to Study the Activity of the Gut Microbiome
Dec 18, 2018 3:00 pm

Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome. The new tools analyze transfer RNA (tRNA), a mo...
Researchers Implement a Massive Sequencing Platform for (DF-PGT) for the First Time in History
Dec 16, 2018 3:00 pm

A research team from the Universitat Autònoma de Barcelona (UAB), in collaboration with the Blood and Tissue Bank of Catalonia, has managed to implement a massive sequencing platform for Pre...
New Research Reveals the Three-Dimensional Structure of the DUX4 Protein Which Is Responsible for Muscular Dystrophy
Dec 15, 2018 4:00 pm

New research by University of Minnesota scientists has revealed the three dimensional structure of the DUX4 protein, which is responsible for the disease, facioscapulohumeral muscular dystrophy (FS...
More
Biopharmaceuticals (98)
NSD2 Might Be a Therapeutic Target for Metastatic and Resistant Prostate Cancers
Dec 9, 2018 6:00 pm

A door opens to a new combined therapy to treat the most aggressive and resistant prostate cancers. This is one of the conclusions reached by researchers from the Institute of Biomedical Research o...
AstraZeneca provides Update on GALATHEA Phase III Trial for Fasenra in Chronic Obstructive Pulmonary Disease
Oct 10, 2018 9:00 am

AstraZeneca and MedImmune, its global biologics research and development arm, today announced top-line results from the GALATHEA Phase III trial for Fasenra (benralizumab) in patients with moderate...
Lumoxiti, the First New Treatment Option for HCL's Patients in Over 20 Years
Sep 26, 2018 12:00 pm

AstraZeneca and MedImmune, its global biologics research and development arm, announced today that the US Food and Drug Administration (FDA) has approved Lumoxiti (moxetumomab pasudotox-tdfk) for the ...
More
Biotechnology (346)
Researchers Develop A High-Throughput RNA Sequencing Strategy to Study the Activity of the Gut Microbiome
Dec 18, 2018 3:00 pm

Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome. The new tools analyze transfer RNA (tRNA), a mo...
Researchers Implement a Massive Sequencing Platform for (DF-PGT) for the First Time in History
Dec 16, 2018 3:00 pm

A research team from the Universitat Autònoma de Barcelona (UAB), in collaboration with the Blood and Tissue Bank of Catalonia, has managed to implement a massive sequencing platform for Pre...
Researchers Discover Several Protein-Coding Genes That Were Misidentified as Non-Protein-Coding
Dec 16, 2018 12:00 pm

The human genome contains regions that “code” for proteins, which means they have instructions to make protein molecules with specific functions in the body. But Yale researchers have d...
More
Cancer (987)
How Does CDK12 Regulate DNA Repair Genes?
Dec 18, 2018 1:00 pm

Mutations in the BRCA1 and BRCA2 genes pose a serious risk for breast and ovarian cancer because they endanger the genomic stability of a cell by interfering with homologous recombination repair (H...
New Mechanism Could Explain How Tumor Cells Kill Their Neighbors and Spread Throughout the Body
Dec 17, 2018 2:00 pm

Despite decades of cancer research, the early phases of tumour progression that connect the appearance of few abnormal cells to the formation of a clinically detectable tumour mass remains poorly u...
The Role of Growth Factors in Malignant Pleural Mesothelioma
Dec 16, 2018 1:00 pm

Malignant pleural mesothelioma is divided into three subtypes, one of which is particularly aggressive. Researchers from the Comprehensive Cancer Center (CCC) of MedUni Vienna and Vienna Gener...
More
Cancer Therapy (386)
How Does CDK12 Regulate DNA Repair Genes?
Dec 18, 2018 1:00 pm

Mutations in the BRCA1 and BRCA2 genes pose a serious risk for breast and ovarian cancer because they endanger the genomic stability of a cell by interfering with homologous recombination repair (H...
The Role of Growth Factors in Malignant Pleural Mesothelioma
Dec 16, 2018 1:00 pm

Malignant pleural mesothelioma is divided into three subtypes, one of which is particularly aggressive. Researchers from the Comprehensive Cancer Center (CCC) of MedUni Vienna and Vienna Gener...
‘Chemo Brain’ Caused by Malfunction in Three Types of Brain Cells
Dec 15, 2018 11:00 am

More than half of cancer survivors suffer from cognitive impairment from chemotherapy that lingers for months or years after the cancer is gone. In a new study explaining the cellular mechanisms be...
More
Cardiology (161)
Researchers Took an Important Step toward the Goal of Making Diseased Hearts Heal Themselves
Dec 17, 2018 12:00 pm

A team of Rutgers scientists, including Leonard Lee and Shaohua Li, have taken an important step toward the goal of making diseased hearts heal themselves – a new model that would reduce the ...
A New Research Reveals Cellular Gene Signatures that Could Be the Key to Understand the Ability of Heart Muscle Repair
Dec 3, 2018 4:00 pm

Repairing heart muscle damaged by a heart attack or other cardiovascular diseases is one of the “holy grails” for cardiovascular scientists. The ability to repair heart muscle – e...
New Research Identifies Two Genes Linked to Tetralogy of Fallot (ToF)
Dec 2, 2018 1:00 pm

Scientists at the University of Manchester have this week published research, funded by the British Heart Foundation (BHF) which shows, for the first time, possible genetic causes of a serious cong...
More
Cell Biology (496)
New Mechanism Could Explain How Tumor Cells Kill Their Neighbors and Spread Throughout the Body
Dec 17, 2018 2:00 pm

Despite decades of cancer research, the early phases of tumour progression that connect the appearance of few abnormal cells to the formation of a clinically detectable tumour mass remains poorly u...
‘Chemo Brain’ Caused by Malfunction in Three Types of Brain Cells
Dec 15, 2018 11:00 am

More than half of cancer survivors suffer from cognitive impairment from chemotherapy that lingers for months or years after the cancer is gone. In a new study explaining the cellular mechanisms be...
How the Partnership between Nucleophosmin and SURF6 Is Influencing the Assembly of Ribosomes?
Dec 13, 2018 4:00 pm

Scientists at St. Jude Children’s Research Hospital have mapped key details of how molecular partners regulate assembly of protein-making factories called ribosomes. The findings, publis...
More
Cell Signaling (139)
An Immune Response Associated with the Development of Idiopathic Scoliosis (IS) Detected in Zebrafish
Dec 18, 2018 12:00 pm

Idiopathic scoliosis (IS) is a complex genetic disorder that affects approximately 4 per cent of children worldwide, yet its underlying biological cause remains unknown. Researchers at The Hos...
Scientists Try to Better Understand the Fundamentals of Blood Glucose Homeostasis and the Pathogenesis of Diabetes
Dec 17, 2018 3:00 pm

A recent study led by researchers in Texas A&M University's department of nutrition and food science shows how a novel regulatory mechanism serves as an important biomarker for the developm...
New Mechanism Could Explain How Tumor Cells Kill Their Neighbors and Spread Throughout the Body
Dec 17, 2018 2:00 pm

Despite decades of cancer research, the early phases of tumour progression that connect the appearance of few abnormal cells to the formation of a clinically detectable tumour mass remains poorly u...
More
Clinical Trials (141)
A New Therapeutic Vaccine for Treating Women with Precancerous Cervical Cells
Dec 12, 2018 1:00 pm

Vanderbilt University Medical Center is participating in an international study to determine the effectiveness of a new therapeutic vaccine for treating women with precancerous changes on the cervi...
CAR-T Cell Therapy for Promising Treatment B-cell Lymphoma
Dec 6, 2018 11:00 am

An international phase-2 trial of a CAR-T cell therapy published in the New England Journal of Medicine (and presented at the ASH annual meeting in San Diego)—found that 52 percent of patient...
New Study Provides Evidence that Ibrutinib Is the Most Effective Treatment for Older Adults With Chronic lymphocytic leukemia CLL
Dec 5, 2018 2:00 pm

Results from an multi-institutional, phase 3 clinical trial show that older patients with chronic lymphocytic leukemia (CLL) have a significantly lower rate of disease progression if treated with t...
More
Dentistry (13)
New Promising Period of Craniofacial Genetics
Jun 27, 2018 11:00 am

Our faces can reveal a lot about us, and now scientists are revealing a lot about faces. PLOS Genetics announces a special collection of papers to highlight recent advances in our understanding of ...
Instead of Filling Cavities, Dentists May Soon Regenerate Teeth
Mar 28, 2018 4:00 pm

For dentists, a cavity is a conundrum—in order to save the tooth they must further damage it. Currently, the primary way to treat a cavity is to excavate the decay and the surrounding area befor...
New Innovative Product To Preserve Oral Health
Dec 7, 2017 12:00 pm

Dentists rely on composite materials to perform restorative procedures, such as filling cavities. Yet these materials, like tooth enamel, can be vulnerable to the growth of plaque, the sticky biofilm ...
More
Dermatology (36)
New Insight into How the Immune System Can Be Hampered When it Comes to Fighting Cancer
Dec 4, 2018 2:00 pm

Over the course of evolution, the immune system has developed effective mechanisms to detect pathogens invading the body from outside and to eliminate them before they can cause major damage. Howev...
Asexual Reproduction Is the Rule for Trichophyton Rubrum
Jul 22, 2018 11:00 am

The sexual habits of Trichophyton rubrum, the fungus that causes athlete’s foot and other kinds of skin and nail infections, were the focus of a study published by Brazilian scientists and inter...
Increased Public's Interest in Melanoma Testing
Jul 17, 2018 10:00 am

TUESDAY, July 10, 2018 (HealthDay News) -- There is moderately high interest in genetic testing for melanoma risk among the general population, according to a study published in the June issue of JAMA...
More
Developmental Biology (156)
Researchers Took an Important Step toward the Goal of Making Diseased Hearts Heal Themselves
Dec 17, 2018 12:00 pm

A team of Rutgers scientists, including Leonard Lee and Shaohua Li, have taken an important step toward the goal of making diseased hearts heal themselves – a new model that would reduce the ...
New Discovery About The Role of Dark Matter in Human Sex Determination
Dec 16, 2018 11:00 am

Medical researchers at Melbourne's Murdoch Children's Research Institute have made a new discovery about how a baby's sex is determined—it's not just about the X-Y chromosomes...
New Research Identifies Two Proteins That Are the Keys to Decide Embryonic Cell Fate
Dec 15, 2018 1:00 pm

Mammalian embryos are unlike those of any other organism as they must grow within the mother’s body. While other animal embryos grow outside the mother, their embryonic cells can get right to...
More
Diabetes (117)
Scientists Try to Better Understand the Fundamentals of Blood Glucose Homeostasis and the Pathogenesis of Diabetes
Dec 17, 2018 3:00 pm

A recent study led by researchers in Texas A&M University's department of nutrition and food science shows how a novel regulatory mechanism serves as an important biomarker for the developm...
Cancer is Associated with an Increased Risk of Diabetes in Cancer Survivors
Sep 22, 2018 12:00 pm

A new retrospective Korean cohort study of more than half a million men and women followed for 10 years shows that a diagnosis of nine types of cancer was associated with a significantly increased ris...
Time-Restricted Feeding May Reverse Diseases Related to Biological Clock Defects
Sep 13, 2018 10:00 am

LA JOLLA—Scientists at the Salk Institute found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic di...
More
Diseases (819)
An Immune Response Associated with the Development of Idiopathic Scoliosis (IS) Detected in Zebrafish
Dec 18, 2018 12:00 pm

Idiopathic scoliosis (IS) is a complex genetic disorder that affects approximately 4 per cent of children worldwide, yet its underlying biological cause remains unknown. Researchers at The Hos...
New Research Reveals the Three-Dimensional Structure of the DUX4 Protein Which Is Responsible for Muscular Dystrophy
Dec 15, 2018 4:00 pm

New research by University of Minnesota scientists has revealed the three dimensional structure of the DUX4 protein, which is responsible for the disease, facioscapulohumeral muscular dystrophy (FS...
Using in Vitro Cell Culture Could Contribute to a New Treatment for Schizophrenia
Dec 3, 2018 11:00 am

Belmont, MAA study recently published in Translational Psychiatry, a Nature journal, has shown how using cultured cells from patients with psychotic disorders, such as schizophrenia, to investigate...
More
Embryology (12)
New Research Identifies Two Proteins That Are the Keys to Decide Embryonic Cell Fate
Dec 15, 2018 1:00 pm

Mammalian embryos are unlike those of any other organism as they must grow within the mother’s body. While other animal embryos grow outside the mother, their embryonic cells can get right to...
The Secret behind Peace Agreement between Foetal Cells and Maternal Immune System
Dec 5, 2018 4:00 pm

The first Human Cell Atlas study of early pregnancy in humans has shown how the function of the maternal immune system is affected by cells from the developing placenta.   Rese...
Scientists Produce Mouse Pups from Two Mothers by Using Stem Cells and Gene Editing
Dec 1, 2018 4:00 pm

Researchers at the Chinese Academy of Sciences were able to produce healthy mice with two mothers that went on to have normal offspring of their own. Mice from two dads were also born but only surv...
More
Endocrinology (36)
LncRNAs Appear to Be Responsible for Fine Regulation of Genes Involved in Prostate Cancer
Aug 9, 2018 10:00 am

In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone (DHT). For this to happen, these ho...
The Latest Test for Thyroid Nodules
Aug 5, 2018 11:00 am

BOSTON — New data on the latest versions of two top genomic sequencing classifiers (GSC) demonstrate the increasing ability of molecular testing to assist in the management of patients with thyr...
Gestational Oral Low-Dose Estradiol-17β May Affect DNA Methylation in Embryos and Adult Offspring
Jul 5, 2018 11:00 am

The public debate on endocrine disrupting chemicals (EDCs) -- exogenous substances that have the same or similar effects as endogenous hormones -- has been going on for some time. Chemicals such as...
More
Epigenetics (100)
The Epigenetic Mechanism Involved in Schizophrenia
Dec 17, 2018 11:00 am

A study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) has identified, for the first time, epigenetic differences between th...
Researchers Find Revolutionary evidence That Epigenetics Works in Archaea
Dec 12, 2018 2:00 pm

University of Nebraska-Lincoln researchers have found revolutionary evidence that an evolutionary phenomenon at work in complex organisms is at play in their single-celled, extreme-loving counterpa...
New Insights into Longevity and Cognition Revealed by Parrot Genome Comparative Analysis
Dec 12, 2018 12:00 pm

Parrots are famously talkative, and a blue-fronted Amazon parrot named Moises—or at least its genome—is telling scientists volumes about the longevity and highly developed cognitive abi...
More
Evolution (126)
Neandertal Genes Shed Light on Endocranial Globularity of Modern Humans
Dec 17, 2018 6:00 pm

A characteristic feature of modern humans is the unusually round skull and brain, in contrast to the elongated shape seen in other human species. By studying Neandertal DNA fragments found in the g...
Researchers Find Revolutionary evidence That Epigenetics Works in Archaea
Dec 12, 2018 2:00 pm

University of Nebraska-Lincoln researchers have found revolutionary evidence that an evolutionary phenomenon at work in complex organisms is at play in their single-celled, extreme-loving counterpa...
New Insights into Longevity and Cognition Revealed by Parrot Genome Comparative Analysis
Dec 12, 2018 12:00 pm

Parrots are famously talkative, and a blue-fronted Amazon parrot named Moises—or at least its genome—is telling scientists volumes about the longevity and highly developed cognitive abi...
More
Featured (580)
How Do Cell Communicate With Each Other? This New Light-Based Technology Is Quantifying Single-Cell Secretion
Dec 13, 2018 3:00 pm

Scientists at the University of York have developed a new technique that uses light to understand how cells communicate in human disease. All cells in the human body communicate with each othe...
Discovering PLEKHG6 Gene That Drives Aspects of Brain Development Differently in Primates Compared to Other Species
Dec 11, 2018 3:00 pm

University of Otago researchers have discovered information about a gene that sets primates – great apes and humans – apart from other mammals, through the study of a rare developmental...
New Immunoassay Technique Measures Extremely Low Concentrations of Small Molecules
Dec 11, 2018 2:00 pm

As medical science has come to understand that the human body is controlled on the molecular level by various proteins, hormones, drugs, and other substances, technologies have developed to detect ...
More
Gastroenterology (65)
Optogenetics Provides a less Toxic Remedy to debilitating gastrointestinal conditions
Sep 10, 2018 11:00 am

A novel light therapy is being investigated as an alternative to prescription drugs to relieve chronic constipation and other intestinal disorders which affect millions of patients around the world. ...
A New Method to Identify Microbial Genes that Make Some Microbes Live in Your Gut
Aug 29, 2018 10:00 am

SAN FRANCISCO, CA—Trillions of tiny microbes and bacteria live in your gut, each with their own set of genes. These gut microbes can have both beneficial and harmful effects on your health, from...
Colon Cancer And The Role Of IGF-1 In Treatment
Jul 28, 2018 2:00 pm

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associate...
More
Gene Therapy (95)
The Largest Study of Its Kind Discovers 11 New Genes Associated with Epilepsy
Dec 13, 2018 12:00 pm

The largest study of its kind, led by international researchers including scientists at RCSI (Royal College of Surgeons in Ireland), has discovered 11 new genes associated with epilepsy. The r...
Removing RCAN1 Gene Might Be A Novel Approach Against Obesity
Dec 6, 2018 11:00 am

It sounds too good to be true, but a novel approach that might allow you to eat as much food as you want without gaining weight could be a reality in the near future. When a single gene known ...
Microparticles Offer a Promising Treatment for Some Blood Disorders
Dec 4, 2018 11:00 am

Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us. Now, a team of University of Delaware resear...
More
General (316)
New Discovery About The Role of Dark Matter in Human Sex Determination
Dec 16, 2018 11:00 am

Medical researchers at Melbourne's Murdoch Children's Research Institute have made a new discovery about how a baby's sex is determined—it's not just about the X-Y chromosomes...
How Do Cell Communicate With Each Other? This New Light-Based Technology Is Quantifying Single-Cell Secretion
Dec 13, 2018 3:00 pm

Scientists at the University of York have developed a new technique that uses light to understand how cells communicate in human disease. All cells in the human body communicate with each othe...
How the Distance of Microbial Competitions Shapes Their Community Structures?
Dec 8, 2018 10:00 am

Inside the microbial communities that populate our world, microbes are fighting for their lives. These tiny organisms are in the soil, in the oceans, and in the human body. Microbes play sever...
More
Genetic Diseases (275)
An Immune Response Associated with the Development of Idiopathic Scoliosis (IS) Detected in Zebrafish
Dec 18, 2018 12:00 pm

Idiopathic scoliosis (IS) is a complex genetic disorder that affects approximately 4 per cent of children worldwide, yet its underlying biological cause remains unknown. Researchers at The Hos...
Researchers Implement a Massive Sequencing Platform for (DF-PGT) for the First Time in History
Dec 16, 2018 3:00 pm

A research team from the Universitat Autònoma de Barcelona (UAB), in collaboration with the Blood and Tissue Bank of Catalonia, has managed to implement a massive sequencing platform for Pre...
New Discovery About The Role of Dark Matter in Human Sex Determination
Dec 16, 2018 11:00 am

Medical researchers at Melbourne's Murdoch Children's Research Institute have made a new discovery about how a baby's sex is determined—it's not just about the X-Y chromosomes...
More
Genetics (1318)
How Does CDK12 Regulate DNA Repair Genes?
Dec 18, 2018 1:00 pm

Mutations in the BRCA1 and BRCA2 genes pose a serious risk for breast and ovarian cancer because they endanger the genomic stability of a cell by interfering with homologous recombination repair (H...
An Immune Response Associated with the Development of Idiopathic Scoliosis (IS) Detected in Zebrafish
Dec 18, 2018 12:00 pm

Idiopathic scoliosis (IS) is a complex genetic disorder that affects approximately 4 per cent of children worldwide, yet its underlying biological cause remains unknown. Researchers at The Hos...
Scientists Discover a Set of Simple Rules That Determine the Precision of CRISPR/Cas9 Genome Editing in Human Cells
Dec 18, 2018 11:00 am

Crick scientists have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells. These rules, published in Molecular Cell, could help to improve the...
More
Genome & Genomics (342)
Researchers Develop A High-Throughput RNA Sequencing Strategy to Study the Activity of the Gut Microbiome
Dec 18, 2018 3:00 pm

Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome. The new tools analyze transfer RNA (tRNA), a mo...
How Does CDK12 Regulate DNA Repair Genes?
Dec 18, 2018 1:00 pm

Mutations in the BRCA1 and BRCA2 genes pose a serious risk for breast and ovarian cancer because they endanger the genomic stability of a cell by interfering with homologous recombination repair (H...
Scientists Discover a Set of Simple Rules That Determine the Precision of CRISPR/Cas9 Genome Editing in Human Cells
Dec 18, 2018 11:00 am

Crick scientists have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells. These rules, published in Molecular Cell, could help to improve the...
More
Gynecology (45)
Only Sequencing Fetal DNA is Enough !!
Aug 11, 2018 12:00 pm

Sequencing the fetal DNA that circulates in a pregnant woman’s blood holds promise for modern genomic medicine, according to a review article by Diana W. Bianchi, M.D., a senior researcher and i...
A Genetic Variation in Progesterone Receptor Might Be Linked to Prematurity Risk
Jun 30, 2018 2:00 pm

Humans have unexpectedly high genetic variation in the receptor for a key pregnancy-maintaining hormone, according to research led by scientists at the Stanford University School of Medicine. The f...
Study Results Shows that a Blood Sample can Estimate Fetal Age and Follow up Growth
Jun 11, 2018 8:00 pm

Measuring RNA fragments in a pregnant woman’s blood gives a reliable estimate of the baby’s due date and can predict if the baby will arrive prematurely, a Stanford-led team has shown. ...
More
Hematology (103)
Uncovering the Unique Drug Susceptibility Patterns in Leukemia Cells Could Lead to Appropriate Treatment for AML
Dec 11, 2018 1:00 pm

Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML). Research on ...
Scientists Succeed in Turning Human Skin Cells into Blood Stem Cells for the First Time
Dec 8, 2018 12:00 pm

Transplantation of blood stem cells, isolated from mobilized peripheral blood or bone marrow, is a widely utilized therapy for a range of inherited and acquired blood disorders. Allogeneic transpla...
Healthy Blood Stem Cells Seem to Have as Many Mutations as Leukemic Cells!
Dec 2, 2018 11:00 am

Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather the location of th...
More
Histopathology (11)
A New Enzyme with an Abnormal Amino Acid in its Structure
Jul 14, 2018 12:00 pm

University of Groningen chemists have created a new enzyme with an unnatural amino acid as its active centre. They made the enzyme by modifying an antibiotic binding protein which normally acts as a b...
How Oncogenic Mutant Cells Lead The War Against Normal Ones To Expand Its Property in Tissue?
Jun 24, 2018 11:00 am

Cells in multicellular tissues adhere to each other. Epithelial tissues on the surface layer of the intestines and skin pack cells into a hexagonal (honeycomb) pattern, with cells adhering tightly ...
Surprising Discoveries Limit the Importance of Apoptosis in Embryonic Development
May 23, 2018 10:00 am

Australian researchers have made a surprise discovery that could rewrite our understanding of the role programmed cell death plays in embryonic development and congenital birth defects. The team sh...
More
Immunology (412)
The Role of JunB, a Key Transcription Factor in Keeping the Immune System at Bay
Dec 18, 2018 2:00 pm

Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and en...
An Immune Response Associated with the Development of Idiopathic Scoliosis (IS) Detected in Zebrafish
Dec 18, 2018 12:00 pm

Idiopathic scoliosis (IS) is a complex genetic disorder that affects approximately 4 per cent of children worldwide, yet its underlying biological cause remains unknown. Researchers at The Hos...
The Relationship between Cellular RNA Processing and an Innate Antiviral Immune Response
Dec 16, 2018 2:00 pm

The RIG-I like receptors (RLRs) are intracellular enzyme sentries that detect viral infection and initiate a first line of antiviral defense. The cellular molecules that activate RLRs in vivo are n...
More
Infectious Diseases (136)
Researchers Reveal Why Some Patients’ Immune Systems Can Resist HIV-1
Dec 5, 2018 1:00 pm

Of the 40 million people around the world infected with HIV, less than one per cent have immune systems strong enough to suppress the virus for extended periods of time. These special immune system...
How Could HIV DNA Be Blocked from Entering the Cell Nucleus?
Dec 4, 2018 1:00 pm

Multiple components of the nuclear pore complex and nuclear import machinery enable a protein called human myxovirus resistance 2 (MX2) to inhibit HIV-1 infection, according to a study published No...
Synthetic DNA-delivered Antibodies Protect Against Ebola in Preclinical Studies
Dec 1, 2018 5:00 pm

Scientists at The Wistar Institute and collaborators have successfully engineered novel DNA-encoded monoclonal antibodies (DMAbs) targeting Zaire Ebolavirus that were effective in preclinical model...
More
Infertility (37)
Researchers Implement a Massive Sequencing Platform for (DF-PGT) for the First Time in History
Dec 16, 2018 3:00 pm

A research team from the Universitat Autònoma de Barcelona (UAB), in collaboration with the Blood and Tissue Bank of Catalonia, has managed to implement a massive sequencing platform for Pre...
New Discovery About The Role of Dark Matter in Human Sex Determination
Dec 16, 2018 11:00 am

Medical researchers at Melbourne's Murdoch Children's Research Institute have made a new discovery about how a baby's sex is determined—it's not just about the X-Y chromosomes...
What Determines Whether You Are Likely to Have a Boy or a Girl Is Inherited
Dec 15, 2018 2:00 pm

A Newcastle University study involving thousands of families is helping prospective parents work out whether they are likely to have sons or daughters. The work by Corry Gellatly, a research s...
More
Microbiology (202)
How the Distance of Microbial Competitions Shapes Their Community Structures?
Dec 8, 2018 10:00 am

Inside the microbial communities that populate our world, microbes are fighting for their lives. These tiny organisms are in the soil, in the oceans, and in the human body. Microbes play sever...
Creating Microbes with an Expanded Genetic Code Can Open Up New Avenues in Synthetic Biology and Protein Engineering
Dec 3, 2018 2:00 pm

Our genetic code is made up of four nucleotide bases, but in recent years, scientists have created microbes that incorporate totally new bases. That has opened up new avenues in synthetic biology a...
New Approach Identifies More Than 6,000 Antibiotic Resistance Genes in Gut Bacteria
Dec 2, 2018 12:00 pm

A study carried out in collaboration with the University of Birmingham has used an innovative approach to identify thousands of antibiotic resistance genes found in bacteria that inhabit the human ...
More
Molecular Biochemistry (500)
How Does CDK12 Regulate DNA Repair Genes?
Dec 18, 2018 1:00 pm

Mutations in the BRCA1 and BRCA2 genes pose a serious risk for breast and ovarian cancer because they endanger the genomic stability of a cell by interfering with homologous recombination repair (H...
Scientists Try to Better Understand the Fundamentals of Blood Glucose Homeostasis and the Pathogenesis of Diabetes
Dec 17, 2018 3:00 pm

A recent study led by researchers in Texas A&M University's department of nutrition and food science shows how a novel regulatory mechanism serves as an important biomarker for the developm...
The Role of Growth Factors in Malignant Pleural Mesothelioma
Dec 16, 2018 1:00 pm

Malignant pleural mesothelioma is divided into three subtypes, one of which is particularly aggressive. Researchers from the Comprehensive Cancer Center (CCC) of MedUni Vienna and Vienna Gener...
More
Molecular Pharmacology (163)
Stearoyl CoA Desaturase Enzyme as a Target for Parkinson Treatment
Dec 6, 2018 12:00 pm

The human brain is rich in lipids. Investigators studying Parkinson's disease (PD) have become increasingly interested in lipids since both molecular and genetic studies have pointed to the dis...
Could HPV Be Treated by A Cancer Drug?
Dec 4, 2018 10:00 am

Preclinical experiments by University of Alabama at Birmingham researchers suggest the cancer drugs vorinostat, belinostat and panobinostat might be repurposed to treat infections caused by human p...
New Study Showed Discovered small molecules Which Are Targeting A Specific Protein in Autoinflammatory Diseases
Jul 21, 2018 9:00 am

EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory ...
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Mycology (8)
Asexual Reproduction Is the Rule for Trichophyton Rubrum
Jul 22, 2018 11:00 am

The sexual habits of Trichophyton rubrum, the fungus that causes athlete’s foot and other kinds of skin and nail infections, were the focus of a study published by Brazilian scientists and inter...
Identification of the Biosynthetic Gene Cluster for Highly Oxygenated Steroids Group Derived from Fungi
Jun 24, 2018 6:00 pm

A group of researchers from Graduate School of Pharmaceutical Sciences at The University of Tokyo and Institute of Traditional Chinese Medicine and Natural Products at Jinan University, identified ...
Fungal Cells Use Surprising Method To Communicate With Each Other!
May 1, 2018 1:00 pm

The idea of microbes joining forces inside your body to wreak havoc and cause disease sounds frightening — and it should. Now, scientists have found that a particular type of fungus does just th...
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Nanotechnology (56)
Based on the HIV Envelope Protein, Scientists Unveil Promising New HIV Vaccine Strategy
Dec 2, 2018 4:00 pm

The new vaccine strategy, described in a paper on November 23 in Science Advances, is based on the HIV envelope protein, Env. This complex, shape-shifting molecule has been notoriously difficult to...
The Advance in the DNA Nanotechnology Field
Sep 26, 2018 12:00 pm

In the journal Nature Communications, Carlos Castro and Ratnasingham Sooryakumar and their colleagues from The Ohio State University report that the control system reduced the response time of prototy...
A synthetic DNA Enzyme Flips Lipids Causing Cancer Cell Death
Jul 10, 2018 10:00 am

A new synthetic enzyme, crafted from DNA rather than protein, flips lipid molecules within the cell membrane, triggering a signal pathway that could be harnessed to induce cell death in cancer cells. ...
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Neurology (672)
An Immune Response Associated with the Development of Idiopathic Scoliosis (IS) Detected in Zebrafish
Dec 18, 2018 12:00 pm

Idiopathic scoliosis (IS) is a complex genetic disorder that affects approximately 4 per cent of children worldwide, yet its underlying biological cause remains unknown. Researchers at The Hos...
The Epigenetic Mechanism Involved in Schizophrenia
Dec 17, 2018 11:00 am

A study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) has identified, for the first time, epigenetic differences between th...
‘Chemo Brain’ Caused by Malfunction in Three Types of Brain Cells
Dec 15, 2018 11:00 am

More than half of cancer survivors suffer from cognitive impairment from chemotherapy that lingers for months or years after the cancer is gone. In a new study explaining the cellular mechanisms be...
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Nutrition (124)
Time-Restricted Feeding May Reverse Diseases Related to Biological Clock Defects
Sep 13, 2018 10:00 am

LA JOLLA—Scientists at the Salk Institute found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic di...
Extra Carbon Dioxide is Making some of the most Important Crops Less Nutritious by changing their Chemical Makeup !!
Aug 28, 2018 1:00 pm

WASHINGTON — When scientists want to figure out how climate change might disrupt the world’s food supplies, they often explore how rising temperatures could shift growing seasons or how mo...
A New Scientific Advisory from the American Heart Association (AHA)
Aug 28, 2018 12:00 pm

In an updated scientific advisory, the American Heart Association (AHA) reaffirms advice that adults consume fish two times per week to help reduce the risk for congestive heart failure, coronary hear...
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Obesity (101)
Removing RCAN1 Gene Might Be A Novel Approach Against Obesity
Dec 6, 2018 11:00 am

It sounds too good to be true, but a novel approach that might allow you to eat as much food as you want without gaining weight could be a reality in the near future. When a single gene known ...
The Largest Genetic Study of Varicose Veins Provide a New Evidence for the Condition
Oct 1, 2018 10:00 am

The taller you are, the more likely you are to develop varicose veins, according to a study led by Stanford University School of Medicine researchers that examined the genes of more than 400,000 peopl...
Time-Restricted Feeding May Reverse Diseases Related to Biological Clock Defects
Sep 13, 2018 10:00 am

LA JOLLA—Scientists at the Salk Institute found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic di...
More
Ophthalmology (40)
Identifying Subtypes of Retinal Ganglion Cells by Single-Cell RNA Sequencing Technologies
Jul 28, 2018 1:00 pm

Single-cell sequencing technologies are filling in fine details in the catalog of life. Researchers at the University of Connecticut Health Center (UConn Health) and The Jackson Laboratory (JAX) ha...
A Genetic Mutation Associated with Neuromyelitis Optica (NMO)
Jun 28, 2018 12:00 pm

Scientists conducting one of the largest full DNA analyses of a rare disease have identified a gene mutation associated with a perplexing brain condition that blinds and paralyzes patients. A ...
The Largest-Ever Genetic Study Identified 161 Genetic Factors for Myopia
Jun 27, 2018 7:00 pm

The international Consortium for Refractive Error and Myopia (CREAM) recently published the largest-ever genetic study of myopia in Nature Genetics. Researchers from the Gutenberg Health Study at t...
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Organizations / Institutions (147)
Agilent's New Chemical Imaging System Represents a Breakthrough in Both Chemical Imaging and Spectral Analysis
Dec 1, 2018 12:00 pm

Agilent Technologies Inc. (NYSE: A) today introduced a new approach to chemical imaging that will bring greater clarity and unprecedented speed to pharmaceutical, biomedical, food, and materials sc...
Merck’s Paired CRISPR Nickases Technique can Help us to Correct Genetic Defects in Gene Therapy Patients
Sep 27, 2018 10:00 am

Darmstadt, Germany, August 15, 2018 – Merck, the vibrant science and technology company, today announced that the Australian Patent Office has allowed the company’s patent application for ...
Alecensa® is a New Roche's Drug as an Initial Treatment for ALK
Sep 23, 2018 10:00 am

Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the China National Drug Administration (CNDA) has granted marketing authorisation for Alecensa® (alectinib) as a monotherapy treatment for p...
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Osteology (23)
A Malfunctioning Gene May Associated with Ankylosing Spondylitis
Sep 4, 2018 11:00 am

A new Michigan State University study has found that a malfunctioning gene associated with a common arthritic disease that often starts in teenagers is now directly linked to the loss of vital immu...
New Drugs from FDA for Osteoarthritis Pain and Hypertension
Jun 28, 2018 5:30 pm

The US Food and Drug Administration (FDA) approved a combination of amlodipine besylate and the nonsteroidal anti-inflammatory drug (NSAID) celecoxib (Consensi, Kitov Pharma) for individuals with o...
Spinal Stimulation Helps Paralyzed Patients Regain Function
May 5, 2018 10:00 am

Once a person has suffered a spinal cord injury, there isn't much to be done except to learn how to live with paralysis and loss of function. That could change, thanks to the work of a team of sci...
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Otolaryngology (4)
New Technique That Will Force The Centromere To Give Up Its Secrets
Dec 11, 2017 3:00 pm

A new technique may force the centromere -- the mysterious stretch of DNA in the center of every chromosome -- to give up its secrets at last. The first test of the approach has yielded clues about th...
How Sleep Apnea Can Be a Risk Factor for Diabetes?
Sep 19, 2017 10:00 am

Sleep apnea, left untreated for even a few days, can increase blood sugar and fat levels, stress hormones and blood pressure, according to a new study of sleeping subjects. This research adds further ...
Sensory cell regeneration, the new path in treating hearing loss.
May 20, 2017 2:00 pm

In an apparent first, St. Jude Children's Research Hospital investigators have used genetic manipulation to regenerate auditory hair cells in adult mice. The research marks a possible advance in t...
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Parasitology (43)
Bone Marrow is a Major Reservoir for P. Vivax Malaria Parasite
Jul 9, 2018 2:00 pm

NEW YORK (Reuters Health) - Beyond blood, bone marrow is a major reservoir of the malaria parasite Plasmodium vivax, according to an international group of researchers. As Dr. Matthias Marti told R...
Two Proteins Recognize and Translate DNA Methylation Marks in Schistosoma Mansoni
Jul 5, 2018 1:00 pm

Two proteins that recognize and translate DNA methylation marks in Schistosoma mansoni are required for growth of adult stem cells in the parasitic flatworm, as well as production of eggs, accordin...
Revealing for the First Time the Evolutionary Path of Plasmodium falciparum !!
Jun 24, 2018 7:00 pm

The evolutionary path of the deadliest human malaria parasite, Plasmodium falciparum, has been revealed for the first time. This parasite is a member of a parasite family called the Laverania that ...
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Pediatrics (85)
Healthy Blood Stem Cells Seem to Have as Many Mutations as Leukemic Cells!
Dec 2, 2018 11:00 am

Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather the location of th...
A New Syndrome Uncovers the First Evidence Linking ODC1 Mutation and Developmental Problems in Humans
Dec 1, 2018 11:00 am

A Michigan State University pediatric researcher and a Spectrum Health physician have identified a new genetic syndrome in a 3-year-old girl who, for more than two years, has gone undiagnosed. ...
Parents should Pay Attention to the Food that they Give to their hereditary fructose intolerance (HFI) Babies
Sep 25, 2018 1:00 pm

Babies with inherited intolerance of fructose face a risk of acute liver failure if they are fed certain widely available formulas containing fructose, pediatricians and geneticists are warning. Ba...
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Pharmacogenetics (26)
A New Approach to Cancer Therapeutics by Targeting the Evolution of Cancer Cells
Dec 8, 2018 1:00 pm

Singapore – A team of scientists from Agency for Science, Technology and Research’s (A*STAR) Genome Institute of Singapore (GIS) has identified a new approach to cancer therapeutics by ...
A New Syndrome Uncovers the First Evidence Linking ODC1 Mutation and Developmental Problems in Humans
Dec 1, 2018 11:00 am

A Michigan State University pediatric researcher and a Spectrum Health physician have identified a new genetic syndrome in a 3-year-old girl who, for more than two years, has gone undiagnosed. ...
Lumoxiti, the First New Treatment Option for HCL's Patients in Over 20 Years
Sep 26, 2018 12:00 pm

AstraZeneca and MedImmune, its global biologics research and development arm, announced today that the US Food and Drug Administration (FDA) has approved Lumoxiti (moxetumomab pasudotox-tdfk) for the ...
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Physiology (30)
The Epigenetic Mechanism Involved in Schizophrenia
Dec 17, 2018 11:00 am

A study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) has identified, for the first time, epigenetic differences between th...
Receiving Genetic Test Information Can Alter Body Physiology
Dec 15, 2018 12:00 pm

Millions of people in the United States alone have submitted their DNA for analysis and received information that not only predicts their risk for disease but, it turns out, in some cases might als...
Parents should Pay Attention to the Food that they Give to their hereditary fructose intolerance (HFI) Babies
Sep 25, 2018 1:00 pm

Babies with inherited intolerance of fructose face a risk of acute liver failure if they are fed certain widely available formulas containing fructose, pediatricians and geneticists are warning. Ba...
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Products & Technologies (592)
Researchers Develop A High-Throughput RNA Sequencing Strategy to Study the Activity of the Gut Microbiome
Dec 18, 2018 3:00 pm

Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome. The new tools analyze transfer RNA (tRNA), a mo...
Researchers Implement a Massive Sequencing Platform for (DF-PGT) for the First Time in History
Dec 16, 2018 3:00 pm

A research team from the Universitat Autònoma de Barcelona (UAB), in collaboration with the Blood and Tissue Bank of Catalonia, has managed to implement a massive sequencing platform for Pre...
How Do Cell Communicate With Each Other? This New Light-Based Technology Is Quantifying Single-Cell Secretion
Dec 13, 2018 3:00 pm

Scientists at the University of York have developed a new technique that uses light to understand how cells communicate in human disease. All cells in the human body communicate with each othe...
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Proteome & Proteomics (34)
A New Research Reveals Cellular Gene Signatures that Could Be the Key to Understand the Ability of Heart Muscle Repair
Dec 3, 2018 4:00 pm

Repairing heart muscle damaged by a heart attack or other cardiovascular diseases is one of the “holy grails” for cardiovascular scientists. The ability to repair heart muscle – e...
The New Switch And Its Biological Uses
Oct 6, 2018 12:00 pm

A biological switch that reliably turns protein expression on at will has been invented by University of Bath and Cardiff University scientists. The switch enables control of genome editing tools that...
Cells know how to Prepare Supplies Needed for Division !!
Sep 24, 2018 12:00 pm

How does a cell know when to divide? We know that hundreds of genes contribute to a wave of activity linked to cell division, but to generate that wave new research shows that cells must first grow...
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Psychology (114)
The Epigenetic Mechanism Involved in Schizophrenia
Dec 17, 2018 11:00 am

A study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) has identified, for the first time, epigenetic differences between th...
The Influence of Microglial Elimination on Preventing Hyper Immune Sensitivity after Stress
Dec 6, 2018 1:00 pm

Using an animal model of chronic stress, researchers at The Ohio State University have shown that the immune cells of the brain, called microglia, hold unique signatures of chronic stress that leav...
Does Your Environment Determine the Result of Your IQ?
Oct 2, 2018 10:00 am

Is there a link between differences in IQ test performance and the activity of certain genes? Researchers from Charité – Universitätsmedizin Berlin have shown that modifications in t...
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Pulmonary & Respiratory Medicine (36)
A Novel New Way to Treat Asthma
Sep 16, 2018 12:00 pm

An invisible particle enters your lungs. The next thing you know breathing becomes difficult. You are having as asthma attack. Asthma is one of the most common and difficult to endure chronic conditio...
Researchers Have Identified a Genetic Bio-markers to Test Asthma Simply & Accurately
Jun 20, 2018 8:00 pm

Mount Sinai researchers have identified a genetic biomarker of asthma that can be tested for using a simple nasal brush and basic follow-up data analysis. This inexpensive diagnostic test can accur...
Study Identifies New Molecular Target For Treating The Deadly Lung Disease "IPF"
May 2, 2018 12:00 pm

Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclini...
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Regenerative Medicine & Cell Therapy (48)
Researchers Took an Important Step toward the Goal of Making Diseased Hearts Heal Themselves
Dec 17, 2018 12:00 pm

A team of Rutgers scientists, including Leonard Lee and Shaohua Li, have taken an important step toward the goal of making diseased hearts heal themselves – a new model that would reduce the ...
Scientists Discover a Group of Genes Involved in Regeneration That Are Kept in Different Species
Dec 8, 2018 2:00 pm

Researchers from the Department of Genetics, Microbiology and Statistics and the Institute of Biomedicine of the University of Barcelona (UB), in collaboration with the Centre for Genomic Regulatio...
Scientists Succeed in Turning Human Skin Cells into Blood Stem Cells for the First Time
Dec 8, 2018 12:00 pm

Transplantation of blood stem cells, isolated from mobilized peripheral blood or bone marrow, is a widely utilized therapy for a range of inherited and acquired blood disorders. Allogeneic transpla...
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Scientists (7)
Dr. Amin Arnaout Recipient of The Prestigious Homer W. Smith Award
May 15, 2018 9:00 am

Dr. Amin Arnaout has been honored by the American Society of Nephrology (ASN) as recipient of the 2018 Homer W. Smith Award​ and recognized as “an individual who has made outstanding contribut...
Dr. Al-Zayani Receives The Venus Medical Award at a Ceremony In India
May 2, 2018 2:00 pm

Dr. Salman Hamad Al-Zayani, the Assistant Professor of Public Health at the College of Medicine and Medical Sciences at the Arabian Gulf University (AGU), has received the Venus International Medical ...
The Brain Prize This Year Goes To Alzheimer's Researchers
Mar 11, 2018 9:00 am

Four dementia scientists have shared this year's 1m Euro brain prize for pivotal work that has changed our understanding of Alzheimer's disease. Profs John Hardy, Bart De Strooper, Michel G...
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Single Nucleotide Polymorphisms (13)
Low Genetic Diversity Put the Singapore Freshwater Crab Under the Threat of Extinction
Jun 24, 2018 4:00 pm

Researchers from NUS and National Parks Board (NParks) have established that the critically endangered Singapore freshwater crab (Johora singaporensis) does not mix or breed between different popul...
Mendelian Randomization Analysis to More Precision and Less Time and Cost
Jun 7, 2018 1:00 pm

The evolution of medicine relies heavily on the results of clinical trials, which while essential, are extremely costly and carry the potential of unintended adverse consequences. Now researchers from...
Mutations Other Than BRCA Can Cause Second Primary Breast Cancer
Jun 6, 2018 5:00 pm

Rates of inherited mutations in genes other than BRCA1/2 are twice as high in breast cancer patients who have had a second primary cancer—including, in some cases, different types of breast c...
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Stem Cells & Cancer Stem Cells (205)
Researchers Took an Important Step toward the Goal of Making Diseased Hearts Heal Themselves
Dec 17, 2018 12:00 pm

A team of Rutgers scientists, including Leonard Lee and Shaohua Li, have taken an important step toward the goal of making diseased hearts heal themselves – a new model that would reduce the ...
New Research Identifies Two Proteins That Are the Keys to Decide Embryonic Cell Fate
Dec 15, 2018 1:00 pm

Mammalian embryos are unlike those of any other organism as they must grow within the mother’s body. While other animal embryos grow outside the mother, their embryonic cells can get right to...
Uncovering the Unique Drug Susceptibility Patterns in Leukemia Cells Could Lead to Appropriate Treatment for AML
Dec 11, 2018 1:00 pm

Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML). Research on ...
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Toxicology (34)
How the Distance of Microbial Competitions Shapes Their Community Structures?
Dec 8, 2018 10:00 am

Inside the microbial communities that populate our world, microbes are fighting for their lives. These tiny organisms are in the soil, in the oceans, and in the human body. Microbes play sever...
Impacts of highly Hazardous Pollutants Dioxins on Plants
Sep 9, 2018 11:00 am

Dioxins are highly hazardous pollutants that have well characterized impacts on both animal and human health. However, the biological effects of dioxins on plants have yet to be described in detail. ...
Prenatal Exposure to the DDT Toxin may be Related to Autism
Sep 4, 2018 10:00 am

National birth cohort study finds DDT metabolites in the blood of pregnant women are associated with elevated odds of autism in offspring. A study of more than 1 million pregnancies in Finland...
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Transcriptome & Transcriptomics (10)
Scientists Discover a Group of Genes Involved in Regeneration That Are Kept in Different Species
Dec 8, 2018 2:00 pm

Researchers from the Department of Genetics, Microbiology and Statistics and the Institute of Biomedicine of the University of Barcelona (UB), in collaboration with the Centre for Genomic Regulatio...
A New Approach to Cancer Therapeutics by Targeting the Evolution of Cancer Cells
Dec 8, 2018 1:00 pm

Singapore – A team of scientists from Agency for Science, Technology and Research’s (A*STAR) Genome Institute of Singapore (GIS) has identified a new approach to cancer therapeutics by ...
A New Research Reveals Cellular Gene Signatures that Could Be the Key to Understand the Ability of Heart Muscle Repair
Dec 3, 2018 4:00 pm

Repairing heart muscle damaged by a heart attack or other cardiovascular diseases is one of the “holy grails” for cardiovascular scientists. The ability to repair heart muscle – e...
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Urology (11)
Genetic Mutations Could Play a Vital Role in Improving Diagnosis of Prostate Cancer Patients
Sep 17, 2018 10:00 am

Scientists have discovered a link between certain genetic mutations, the aggressiveness of prostate cancer, risk of developing the disease and poorer survival rates of patients. The gene, called ANO7,...
Disabled Kidney Function May Cause Diabetes
Dec 16, 2017 4:00 pm

Diabetes is known to increase a person's risk of kidney disease. Now, a new study from Washington University School of Medicine in St. Louis suggests that the converse also is true: Kidney dysfunc...
Rare resistance mutation reduces treatment choices for urinary tract infections
Sep 9, 2017 6:00 pm

Nearly 20 percent of women aged 15-29 are diagnosed with a urinary tract infection (UTI). Now, investigators have uncovered a rare mutation that renders a UTI-causing pathogen resistant to levofloxaci...
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Vaccines (54)
A New Therapeutic Vaccine for Treating Women with Precancerous Cervical Cells
Dec 12, 2018 1:00 pm

Vanderbilt University Medical Center is participating in an international study to determine the effectiveness of a new therapeutic vaccine for treating women with precancerous changes on the cervi...
Based on the HIV Envelope Protein, Scientists Unveil Promising New HIV Vaccine Strategy
Dec 2, 2018 4:00 pm

The new vaccine strategy, described in a paper on November 23 in Science Advances, is based on the HIV envelope protein, Env. This complex, shape-shifting molecule has been notoriously difficult to...
Novel Approach Has the Potential to Measure the Effectiveness of Bexsero More Accurately
Jun 21, 2018 1:00 pm

Researchers at Leicester and the Meningococcal Reference Unit have developed a new approach to assess the effectiveness of the Men B vaccine, Bexsero®, against different strains that cause meni...
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Virology (195)
“Block and Lock” Strategy to Control HIV Latency through Manipulation of Tat Gene Circuit
Dec 10, 2018 4:00 pm

A new study suggests that a genetic switch that causes latent HIV inside cells to begin to replicate can be manipulated to completely eradicate the virus from the human body. Cells harboring latent...
The Role of Cellular Protein CK1-alpha in the Replication of Rotavirus
Dec 6, 2018 3:00 pm

Rotaviruses, like all viruses, reproduce inside living cells. Making new viruses requires assembling replication factories via a complex, little known process that involves both viral and cellular ...
Researchers Reveal Why Some Patients’ Immune Systems Can Resist HIV-1
Dec 5, 2018 1:00 pm

Of the 40 million people around the world infected with HIV, less than one per cent have immune systems strong enough to suppress the virus for extended periods of time. These special immune system...
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