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Molecular basis of human obesity - literature review

17th February, 2017
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Abstract Obesity has become a serious health problem as well as economic and social challenge in the highly developed societies. In 2010 there were over 1 billion overweight people worldwide and ca. 475 million were classified as obese with the BMI ≥ 30. That global health problem became an alarming issue affecting developed and developing countries alike. Genetic factors are attributed a special role in the etiopathogenesis of obesity. Recent data suggest that mutations and polymorphism identified in various genes contribute to a higher predisposition to obesity. In this review, we focus on the human mono- and polygenic obesity syndromes. The purpose of this work is to present, based on the literature review, the most recent findings concerning genetic causes of obesity. Keywords: Body Mass Index, Human obesity, Genetic markers, Mutation, Polymorphism


GeneticsObesity



TMKARPI?SKI PUBLISHER


2013


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Citation: Tomaszewska A., Kopczyński P., Flieger R. and Thielemann A. Molecular basis of human obesity - literature review. J Bi ol Earth Sci. (2013); 3(2):M48-M51.

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